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dc.contributor.author김영희-
dc.creator김영희-
dc.date.accessioned2016-08-26T02:08:30Z-
dc.date.available2016-08-26T02:08:30Z-
dc.date.issued1983-
dc.identifier.otherOAK-000000000163-
dc.identifier.urihttps://dspace.ewha.ac.kr/handle/2015.oak/191924-
dc.identifier.urihttp://dcollection.ewha.ac.kr/jsp/common/DcLoOrgPer.jsp?sItemId=000000000163-
dc.description.abstract蔓蔘 Codonopsis pilosula(Franchet) Nannfeldt(Campanulaceae)의 ether soluble fraction에서 5가지 物質 ( 化合物 1, 2, 3, 4, 5 )을 分離하여서 여러가지 理化學的 實驗 및 機器分析 Data를 綜合하여 이들의 化學構造를 Taraxeryl Acetate, mp 298-301˚, [α] `_18^D = +10.5˚(c=0.8, CHCI_3), Friedelin, mp 263-5˚, [α] `_18^D = -25.5˚(c=0.5, CHCI_3), Taraxerol, mp 287-8˚, [α] `_18^D = ±0(c=0.81,CHCI_3), α-Spinasterol, mp 165-7˚, [α] `_20^D = -4.5˚(c=0.5, CHCI_3) 및 α-Spinasteryl-β-D-glucoside, mp 283-5˚, [α] `_20^D = -37.5 ˚(c=0.25, DMF)임을 밝혔다. α-Spinasterol과 α-Spinasteryl-β-D-glucoside에는 少量의 △^7-Stigmastenol 및 △^7-Stigmastenyl-β-D-glucoside가 名名 混合되어 있음을 spectral data를 통하여 確認하였다. ; The root of Codonopsis pilosula (Franchet) Nannfeldt (Campanulaceae) has been used as a folk medicine in treating hyperpiesia, anemia and leukemia or as a substitute for Korean ginseng in traditional oriental medicine. Repeated column chromatography on silica gel of the ether-soluble constituents of the dried root resulted in the isolation of three Triterpenoids, Taraxeryl Acetate, mp 298-301˚, Friedelin, mp 263-5˚, and Taraxerol, mp 287-8˚ together with α-Spinasterol, mp 165-7˚ and its Glucoside, mp 283-5˚. All compounds were identified on the basis of spectral data and chemical reactions. Spectral data showed that △^7-Stigmastenol and its Glucoside were contained in α-Spinasterol and its Glucoside, respectively, as a minor component.-
dc.description.tableofcontentsⅠ. 緖論 ------------------------------------------------------------- 1 Ⅱ. 實驗 ------------------------------------------------------------- 3 1. 抽出 및 分離 ----------------------------------------------------- 3 2. 化合物 1 --------------------------------------------------------- 3 3. 化合物 2 --------------------------------------------------------- 4 4. 化合物 3 --------------------------------------------------------- 5 5. 化合物 4 --------------------------------------------------------- 5 6. 化合物 5 --------------------------------------------------------- 6 7. 化合物 1의 Saponification ---------------------------------------- 7 8. 化合物 1의 酸處理 ------------------------------------------------ 7 9. 化合物 3의 Acetylation ------------------------------------------- 8 10. 化合物 3의 酸處理 ----------------------------------------------- 8 11. 化合物 6의 Acetylation ------------------------------------------ 9 12. 化合物 5의 酸加水分解 ------------------------------------------- 9 13. 化合物 5의 Acetylation ------------------------------------------ 10 Ⅲ. 結果 및 考察 ----------------------------------------------------- 11 Ⅳ. 結論 ------------------------------------------------------------- 33 參考文獻 ------------------------------------------------------------- 34 英文抄錄 ------------------------------------------------------------- 38-
dc.formatapplication/pdf-
dc.format.extent860708 bytes-
dc.languagekor-
dc.publisher이화여자대학교 대학원-
dc.title만삼의 성분 연구-
dc.typeDoctoral Thesis-
dc.identifier.thesisdegreeDoctor-
dc.identifier.major대학원 약학과-
dc.date.awarded1983. 8-
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