2015 | Synthesis and biological evaluation of 5-(fluoro-substituted-6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-alpha]pyridin-6-yl)imidazoles as inhibitors of transforming growth factor-beta type I receptor kinase | 신윤용; 김대기 | Article |
2016 | TGF-β type i receptor kinase inhibitor EW-7197 suppresses cholestatic liver fibrosis by inhibiting HIF1α-induced epithelial mesenchymal transition | 신윤용; 김대기 | Article |
2012 | Synthesis and biological evaluation of 2-benzylamino-4(5)-(6-methylpyridin- 2-yl)-5(4)-([1,2,4]triazolo[1,5-a]-pyridin-6-yl)thiazoles as transforming growth factor-β type 1 receptor kinase inhibitors | 신윤용; 김대기; 김승원 | Article |
2014 | 4-([1,2,4]Triazolo[1,5-a]pyridin-6-yl)-5(3)-(6-methylpyridin-2-yl)imidazole and -pyrazole derivatives as potent and selective inhibitors of transforming growth factor-β type i receptor kinase | 신윤용; 김대기 | Article |
2012 | Anti-cancer effect of IN-2001 in MDA-MB-231 human breast cancer | 신윤용; 김대기 | Article |
2012 | Anti-cancer effect of in-2001 in T47D human breast cancer | 신윤용; 김대기 | Article |
2014 | An novel inhibitor of TGF-β type I receptor, IN-1130, blocks breast cancer lung metastasis through inhibition of epithelial-mesenchymal transition | 신윤용; 김대기 | Article |
2014 | Discovery of N-((4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin- 2-yl)-1H-imidazol-2-yl)methyl)-2-fluoroaniline (EW-7197): A highly potent, selective, and orally bioavailable inhibitor of TGF-β type I receptor kinase as cancer immunotherapeutic/antifibrotic agent | 신윤용; 이화정; 김대기 | Article |
2011 | EW-7203, a novel small molecule inhibitor of transforming growth factor-β (TGF-β) type I receptor/activin receptor-like kinase-5, blocks TGF-β1-mediated epithelial-to-mesenchymal transition in mammary epithelial cells | 신윤용; 김대기 | Article |
2015 | Combinatorial TGF-beta attenuation with paclitaxel inhibits the epithelial-to-mesenchymal transition and breast cancer stem-like cells | 신윤용; 김대기; 임우성 | Article |