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Showing results 1 to 30 of 73

Issue DateTitleAuthor(s)Type
20073D-QSAR studies on sildenafil analogues, selective phosphodiesterase 5 inhibitors김대기Article
20144-([1,2,4]Triazolo[1,5-a]pyridin-6-yl)-5(3)-(6-methylpyridin-2-yl)imidazole and -pyrazole derivatives as potent and selective inhibitors of transforming growth factor-β type i receptor kinase신윤용; 김대기Article
2012A-62176, a potent topoisomerase inhibitor, inhibits the expression of human epidermal growth factor receptor 2김대기; 권영주; 전규연Article
2013Activin receptor-like kinase5 inhibition suppresses mouse melanoma by ubiquitin degradation of Smad4, thereby derepressing eomesodermin in cytotoxic T lymphocytes김대기Article
2009Altered bone morphogenetic protein and transforming growth factor-β signaling in rat models of pulmonary hypertension. Potential for activin receptor-like kinase-5 inhibition in prevention and progression of disease김대기Article
2014An novel inhibitor of TGF-β type I receptor, IN-1130, blocks breast cancer lung metastasis through inhibition of epithelial-mesenchymal transition신윤용; 김대기Article
2012Anti-cancer effect of IN-2001 in MDA-MB-231 human breast cancer신윤용; 김대기Article
2012Anti-cancer effect of in-2001 in T47D human breast cancer신윤용; 김대기Article
2004Antiproliferative effect of trichostatin A and HC-toxin in T47D human breast cancer cells신윤용; 김대기Article
2015Antitubercular activities of the novel synthesized 1,2,4-triazole derivatives신윤용; 박혜영; 김대기Article
2023Beneficial Effects of a Curcumin Derivative and Transforming Growth Factor-β Receptor I Inhibitor Combination on Nonalcoholic Steatohepatitis김대기Article
2017Cancer upregulated gene 2 induces epithelial-mesenchymal transition of human lung cancer cells via TGF-beta signaling김대기Article
2015Combinatorial TGF-beta attenuation with paclitaxel inhibits the epithelial-to-mesenchymal transition and breast cancer stem-like cells신윤용; 김대기; 임우성Article
2015Combinatorial TGF-β attenuation with paclitaxel inhibits the epithelial-to-mesenchymal transition and breast cancer stem-like cells신윤용; 김대기; 임우성Article
2004Design, synthesis, and biological evaluation of novel 2-pyridinyl-[1,2,4] triazoles as inhibitors of transforming growth factor β1 type 1 receptor김대기Article
2007Development of 4(5)-(6-alkylpyridin-2-yl)imidazoles as transforming growth factor-beta type1 receptor kinase inhibitors as anti-fibrotic agents김대기Meeting Abstract
2007Development of LC/MS/MS assay for the determination of 5-ethyl-2-{5-[4-(2-hydroxyethyl)piperazine-1-sulfonyl]-2-propoxyphenyl}-7-propyl-3,5-dihydropyrrolo[3,2-d]pyrimidin-4-one (SK3530) in human plasma: application to a clinical pharmacokinetic study김대기Article
2023Different routes of administering EW-7197 versus EW-7197⋅HBr for preventing peritoneal adhesion in a rat model김대기Article
2022Discovery of (E)-3-(3-((2-Cyano-4' -dimethylaminobiphenyl-4-ylmethyl)cyclohexanecarbonylamino)-5-fluorophenyl)acrylic Acid Methyl Ester, an Intestine-Specific, FXR Partial Agonist for the Treatment of Nonalcoholic Steatohepatitis이화정; 김대기; 권영주; 최선; 박서정Article
2022Discovery of an Intestine-specific FXR Partial Agonist for the Treatment of Nonalcoholic Steatohepatitis심소연Doctoral Thesis
2014Discovery of N-((4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin- 2-yl)-1H-imidazol-2-yl)methyl)-2-fluoroaniline (EW-7197): A highly potent, selective, and orally bioavailable inhibitor of TGF-β type I receptor kinase as cancer immunotherapeutic/antifibrotic agent신윤용; 이화정; 김대기Article
2008DISTRIBUTION AND METABOLISM OF NEW ALK-5 INHIBITOR, IN-1130신윤용; 김대기Meeting Abstract
2008Effect of IN-1130, a Small Molecule Inhibitor of Transforming Growth Factor-beta Type I Receptor/Activin Receptor-Like Kinase-5, on Prostate Cancer Cells신윤용; 김대기Article
2001Effect of SKI 306X, a New herbal anti-arthritic agent, in patients with osteoarthritis of the knee: a double-blind placebo controlled study노권재; 김대기Article
2004Estrogen receptor enhances the anti proliferative effects of trichostatin a and HC-toxin in human breast cancer cells신윤용; 김대기Article
2011EW-7195, a novel inhibitor of ALK5 kinase inhibits EMT and breast cancer metastasis to lung신윤용; 김대기Article
2018EW-7197 eluting nano-fiber covered self-expandable metallic stent to prevent granulation tissue formation in a canine urethral model김대기Article
2014EW-7197 inhibits hepatic, renal, and pulmonary fibrosis by blocking TGF-β/Smad and ROS signaling신윤용; 김대기; 우현애Article in Press
2014EW-7197, a novel ALK-5 kinase inhibitor, potently inhibits breast to lung metastasis신윤용; 김대기Article
2017EW-7197, an activin-like kinase 5 inhibitor, suppresses granulation tissue after stent placement in rat esophagus김대기Article

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