Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 윤주영 | - |
dc.contributor.author | 장원준 | - |
dc.date.accessioned | 2024-08-30T16:31:11Z | - |
dc.date.available | 2024-08-30T16:31:11Z | - |
dc.date.issued | 2024 | - |
dc.identifier.issn | 3270-2700 | - |
dc.identifier.other | OAK-35594 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/269553 | - |
dc.description.abstract | Developing a novel strategy to improve the optical performances of fluorescent probes is a vital factor in elevating its practical application; viz., novel biocompatible fluorescent probes with excellent multifunctions exhibited unparalleled advantages in probing functions of intracellular molecules to elucidate intracellular events in living systems. Herein, we have successfully constructed a new strategy that aggregation and coordination synergistically induce (2-hydroxylphenyl-benzothiazole) HBT derivatives to form excimers with large red-shifted fluorescence and application for insight into stress-response zinc fluctuations in living systems. We have synthesized four HBT-based derivatives and deeply investigated the response mechanism by fluorescent spectral studies, demonstrating that probes 3 and 4 showcased large red shifts in emission wavelength due to J-aggregation. More interestingly, the fluorescence of probe 4 was significantly enhanced in the presence of a zinc ion, suggesting that zinc coordination synergistically induced J-aggregation. Probe 4 was successfully applied to image zinc fluctuations in different models of living systems, proving that this probe is a powerful tool to unveil the relationship between invasive stress and diseases by monitoring endogenous zinc fluctuations. © 2024 American Chemical Society. | - |
dc.description.sponsorship | American Chemical Society | - |
dc.language | English | - |
dc.title | Coordination Synergistic-Induced J-Aggregation Enhanced Fluorescent Performance of HBT-Excimers and Imaging Applications | - |
dc.type | Article | - |
dc.relation.issue | 31 | - |
dc.relation.volume | 96 | - |
dc.relation.index | SCIE | - |
dc.relation.index | SCOPUS | - |
dc.relation.startpage | 12794 | - |
dc.relation.lastpage | 12800 | - |
dc.relation.journaltitle | Analytical Chemistry | - |
dc.identifier.doi | 10.1021/acs.analchem.4c02152 | - |
dc.identifier.wosid | WOS:001279697000001 | - |
dc.identifier.scopusid | 2-s2.0-85199545969 | - |
dc.author.google | Liu | - |
dc.author.google | Shudi | - |
dc.author.google | Fang | - |
dc.author.google | Shujing | - |
dc.author.google | Jang | - |
dc.author.google | Won Jun | - |
dc.author.google | Yoon | - |
dc.author.google | Juyoung | - |
dc.author.google | Zhang | - |
dc.author.google | Liangwei | - |
dc.contributor.scopusid | 윤주영(7403587371) | - |
dc.contributor.scopusid | 장원준(57188580613) | - |
dc.date.modifydate | 20240830115805 | - |