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Long-term clinical impact of early recurrence of atrial tachyarrhythmia after cryoballoon ablation in patients with atrial fibrillation
- Title
- Long-term clinical impact of early recurrence of atrial tachyarrhythmia after cryoballoon ablation in patients with atrial fibrillation
- Authors
- Park; Jinsun; Cha; Myung-Jin; Kwon; Chang Hee; Cho; Min Soo; Nam; Gi-Byoung; Oh; Il-Young; Lee; So-Ryoung; Kim; Ju Youn; Sung Ho; Junbeom; Ki-Hun; Yang; Pil-Sung; Jun Hyung; Shim; Jaemin; Lim; Hong Euy
- Ewha Authors
- 박준범
- SCOPUS Author ID
- 박준범
- Issue Date
- 2024
- Journal Title
- Journal of Cardiovascular Electrophysiology
- ISSN
- 1045-3873
- Citation
- Journal of Cardiovascular Electrophysiology vol. 35, no. 8, pp. 1614 - 1623
- Keywords
- atrial fibrillation; blanking period; cryoballoon ablation; recurrence
- Indexed
- SCIE; SCOPUS
- Document Type
- Article
- Abstract
- Introduction: The impact of early recurrence of atrial tachyarrhythmia (ERAT) within the 90-day blanking period on long-term outcomes in atrial fibrillation (AF) patients undergoing cryoballoon ablation (CBA) is controversial. This study aimed to assess the relationship between ERAT and late recurrence of atrial tachyarrhythmia (LRAT) post-CBA. Methods: Utilizing data from a multicenter registry in Korea (May 2018 to June 2022), we analyzed the presence and timing of ERAT (<30, 30–60, and 60–90 days) and its association with LRAT risk after CBA. LRAT was defined as any recurrence of AF, atrial flutter, or atrial tachycardia lasting more than 30 s beyond the 90 days. Results: Out of 2636 patients, 745 (28.2%) experienced ERAT post-CBA. Over an average follow-up period of 21.2 ± 10.3 months, LRAT was observed in 874 (33.1%) patients. Patients with ERAT had significantly lower 1-year LRAT freedom compared to those without ERAT (42.6% vs. 85.5%, p <.001). Multivariate analysis identified ERAT as a potential predictor of LRAT, with a hazard ratio (HR) of 3.98 (95% confidence interval [CI], 3.47–4.57). Significant associations were noted across all examined time frames (HR, 3.84; 95% CI, 3.32–4.45 in <30 days, HR, 5.53; 95% CI, 4.13–7.42 in 30–60 days, and HR, 4.29; 95% CI, 3.12–5.89 in 60–90 days). This finding was consistently observed across all types of AF. Conclusion: ERAT during the 90-day blanking period strongly predicts LRAT in AF patients undergoing CBA, indicating a need to reconsider the clinical significance of this period. © 2024 The Author(s). Journal of Cardiovascular Electrophysiology published by Wiley Periodicals LLC.
- DOI
- 10.1111/jce.16334
- Appears in Collections:
- 의과대학 > 의학과 > Journal papers
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