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Work-related asthma in adults with severe asthma from the Korean Severe Asthma Registry (KoSAR)
- Title
- Work-related asthma in adults with severe asthma from the Korean Severe Asthma Registry (KoSAR)
- Authors
- Lee; Youngsoo; Sun-Kyung; Park; So-Young; Kim; Min-Hye; Kang; Sung-Yoon; Ban; Ga-Young; Nam; Young-Hee; Joo-Hee; Rhee; Chin Kook; Song; Woo-Jung; Kwon; Jae-Woo; Taehoon; So Ri; Heung-Woo; Cho; You Sook; Koh; Young-Il; Yoo; Kwang-Ha; Byung-Jae; Yoon; Ho Joo; Hae-Sim; Sang-Heon
- Ewha Authors
- 김민혜
- SCOPUS Author ID
- 김민혜
![scopus](/images/layout/icon2.png)
- Issue Date
- 2024
- Journal Title
- World Allergy Organization Journal
- ISSN
- 1939-4551
- Citation
- World Allergy Organization Journal vol. 17, no. 5
- Keywords
- Anxiety; Depression; Quality of life; Severe asthma; Work-related asthma
- Indexed
- SCIE; SCOPUS
![scopus](/images/layout/scopus2.gif)
- Document Type
- Article
- Abstract
- Background: Exposure to allergens or irritants in the workplace may affect asthma control and the quality of life (QoL) of patients with asthma. Objective: To examine the prevalence and characteristics of work-related asthma (WRA) in adult patients with severe asthma. Methods: We analyzed data from the Korean Severe Asthma Registry (KoSAR), which is a nationwide multicenter observational study on severe asthma in Korea. Severe asthma was defined according to the American Thoracic Society (ATS) and the European Respiratory Society (ERS) guidelines. WRA was identified on the basis of asthma symptom aggravation at the workplace, as indicated by responses to a structured questionnaire. We compared the demographic and clinical characteristics and QoL between adult patients with severe asthma and WRA and those without WRA. Results: Among 364 patients with severe asthma who were employed at the time of enrollment, 65 (17.9%) had WRA. There were no significant differences in age, sex, obesity, or smoking history between the WRA and non-WRA groups. However, individuals with WRA exhibited a higher prevalence of anxiety (7.7% vs 2.4%, P = 0.046) and depression (12.3% vs 3.7%, P = 0.010) than those without. The levels of asthma control, lung function, and frequency of asthma exacerbations were similar between the two groups, but patients with WRA reported lower QoL, as determined by the Quality of Life Questionnaire for Adult Korean Asthmatics (56.6 ± 14.6 vs. 63.5 ± 13.9, P < 0.001). Conclusion: Patients with severe asthma and WRA are more likely to experience anxiety and depression and have lower QoL than those without WRA. © 2024 The Authors
- DOI
- 10.1016/j.waojou.2024.100903
- Appears in Collections:
- 의과대학 > 의학과 > Journal papers
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