Full metadata record
DC Field | Value | Language |
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dc.contributor.author | Ansari Abuzar | - |
dc.date.accessioned | 2024-08-26T16:30:03Z | - |
dc.date.available | 2024-08-26T16:30:03Z | - |
dc.date.issued | 2024 | - |
dc.identifier.issn | 1612-1872 | - |
dc.identifier.other | OAK-35853 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/269298 | - |
dc.description.abstract | Background: Alpinia calcarata (AC) Roscoe of Zingiberaceae popularly known as lesser galangal has a widespread occurrence in China, India, Sri-Lanka, Bangladesh, Malaysia, Indonesia and Thailand. Essential oil (Eoil) was obtained from leaves/rhizomes of AC via hydro-distillation process. Methods: To identify chemical ingredients in oil from leaves/rhizomes of AC through GC/MS technique for volatile components and their anti-oxidant, inflammatory/diabetic activities. Results: The 38 and 65 components were found to make up 99.9 and 99.6 %, respectively in total of Eoil composition of AC leaves/rhizomes. Key chemical constituents were eucalyptol (28.7 % in leaves; 25.4 % in rhizomes), camphor (12.8 % in leaves; 4.2 % in rhizomes), and carotol (9.8 % in leaves; 5.6 % in rhizomes) found in oil of AC leaves/rhizomes. Colorimetric assay showed anti-oxidant activities in leaves and rhizomes are IC50=71.01±0.71 μg/mL and IC50=73.83±0.49 μg/mL, respectively in the Eoils. Eoils had high anti-oxidant capabilities in IC50-values of AC-L-Eoil=43.09±0.82&AC-Rh-Eoil=68.11±0.87 in reducing power in μg/mL was found. Albumin test of rhizome oil had IC50-values of 15.19±0.25 μg/mL. Concentrations range of 7.81 μg/mL and 250 μg/mL in the Eoils of AC leaves and rhizome, respectively by α-glucosidase inhibition assay. Conclusion: Our findings demonstrated that leaf oil was slightly more promising results than rhizome oil of AC extract, which was ultimately showed medicinal potential of secondary metabolites with anti-oxidant, diabetic/inflammatory activities. Further, Eoils of AC have a wide range of pharmacological potential and promising anti-diabetic effects. © 2023 Wiley-VHCA AG, Zurich, Switzerland. | - |
dc.description.sponsorship | John Wiley and Sons Inc | - |
dc.language | English | - |
dc.subject | Alpinia calcarata | - |
dc.subject | Antidiabetic | - |
dc.subject | Eoils | - |
dc.subject | Eucalyptol | - |
dc.subject | GC/MS | - |
dc.title | Antioxidant, Diabetic and Inflammatory Activities of Alpinia calcarata Roscoe Extract | - |
dc.type | Article | - |
dc.relation.issue | 6 | - |
dc.relation.volume | 21 | - |
dc.relation.index | SCIE | - |
dc.relation.index | SCOPUS | - |
dc.relation.journaltitle | Chemistry and Biodiversity | - |
dc.identifier.doi | 10.1002/cbdv.202300970 | - |
dc.identifier.scopusid | 2-s2.0-85173925407 | - |
dc.author.google | Devi | - |
dc.author.google | Naorem Manglembi | - |
dc.author.google | Nagarajan | - |
dc.author.google | Sankaranarayanan | - |
dc.author.google | Singh | - |
dc.author.google | Chingakham Brajakishor | - |
dc.author.google | Khan | - |
dc.author.google | Mohammad Mujahid Ali | - |
dc.author.google | Anish | - |
dc.author.google | Nisha | - |
dc.author.google | Mahmoud | - |
dc.author.google | Mohamed H. | - |
dc.author.google | Fouad | - |
dc.author.google | Hassan | - |
dc.author.google | Ansari | - |
dc.author.google | AbuZar | - |
dc.contributor.scopusid | Ansari Abuzar(57193923656) | - |
dc.date.modifydate | 20240826111053 | - |