Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김경희 | * |
dc.contributor.author | 김혜순 | * |
dc.contributor.author | 박혜숙 | * |
dc.contributor.author | 이혜아 | * |
dc.contributor.author | 이로지 | * |
dc.contributor.author | 최정은 | * |
dc.date.accessioned | 2024-05-17T16:31:20Z | - |
dc.date.available | 2024-05-17T16:31:20Z | - |
dc.date.issued | 2024 | * |
dc.identifier.issn | 2227-9067 | * |
dc.identifier.other | OAK-35024 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/268325 | - |
dc.description.abstract | Aim: This study investigated the sex-specific association between thyroid function and various insulin resistance (IR) indices, including noninsulin-based IR indices, in euthyroid adolescents. Methods: A total of 465 adolescents (aged 12–18 years; 255 boys and 210 girls) based on data from the 2014–2015 Korea National Health and Nutrition Examination Survey were included. Serum thyrotropin (thyroid-stimulating hormone [TSH]) and free thyroxine (fT4) were used to assess thyroid function, whereas the homeostasis model assessment of insulin resistance (HOMA-IR), quantitative insulin-sensitivity check index (QUICKI), glucose/insulin ratio (GIR), triglyceride–glucose (TyG) index, and triglyceride/high-density lipoprotein cholesterol (TG/HDL-C) ratio were used to assess IR. The relationship between thyroid function and IR was analyzed using multiple linear regressions stratified by sex, considering obesity status. Results: The relationship between thyroid function and IR varied depending on sex and was more pronounced in the overweight/obesity subgroup for both boys and girls. In overweight and obese boys and girls, fT4 was significantly associated with HOMA-IR and QUICKI with conflicting association directions. TSH was also positively associated with the TyG index in both sexes. Conclusions: The findings suggest that the relationship between thyroid function and IR in adolescents might vary depending on sex, and the degree of association was significant in obese adolescents. © 2024 by the authors. | * |
dc.language | English | * |
dc.publisher | Multidisciplinary Digital Publishing Institute (MDPI) | * |
dc.subject | adolescent | * |
dc.subject | insulin resistance | * |
dc.subject | Korea National Health and Nutrition Examination Survey (KNHANES) | * |
dc.subject | thyroid function | * |
dc.title | Association between Thyroid Function and Insulin Resistance Indices in Korean Adolescents: Findings from the 2014–2015 Korea National Health and Nutrition Examination Survey | * |
dc.type | Article | * |
dc.relation.issue | 3 | * |
dc.relation.volume | 11 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.journaltitle | Children | * |
dc.identifier.doi | 10.3390/children11030370 | * |
dc.identifier.wosid | WOS:001191781700001 | * |
dc.identifier.scopusid | 2-s2.0-85188741798 | * |
dc.author.google | Mun | * |
dc.author.google | Eunji | * |
dc.author.google | Lee | * |
dc.author.google | Hye Ah | * |
dc.author.google | Choi | * |
dc.author.google | Jung Eun | * |
dc.author.google | Rosie | * |
dc.author.google | Kim | * |
dc.author.google | Kyung Hee | * |
dc.author.google | Park | * |
dc.author.google | Hyesook | * |
dc.author.google | Hae Soon | * |
dc.contributor.scopusid | 김경희(55651545100) | * |
dc.contributor.scopusid | 김혜순(55663596500) | * |
dc.contributor.scopusid | 박혜숙(57201862679;56148186100) | * |
dc.contributor.scopusid | 이혜아(57188947704) | * |
dc.contributor.scopusid | 최정은(57200341391) | * |
dc.date.modifydate | 20240607120204 | * |