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A network-based approach to explore comorbidity patterns among community-dwelling older adults living alone
- Title
- A network-based approach to explore comorbidity patterns among community-dwelling older adults living alone
- Authors
- Lee; Chiyoung; Park; Yeon-Hwan; Cho; Belong; Hye Ah
- Ewha Authors
- 이혜아
- SCOPUS Author ID
- 이혜아
- Issue Date
- 2024
- Journal Title
- GeroScience
- ISSN
- 2509-2715
- Citation
- GeroScience vol. 46, no. 2, pp. 2253 - 2264
- Keywords
- Aged; Chronic disease; Comorbidity; Network analysis
- Publisher
- Springer Science and Business Media Deutschland GmbH
- Indexed
- SCIE; SCOPUS
- Document Type
- Article
- Abstract
- The detailed comorbidity patterns of community-dwelling older adults have not yet been explored. This study employed a network-based approach to investigate the comorbidity patterns of community-dwelling older adults living alone. The sample comprised a cross-sectional cohort of adults 65 or older living alone in a Korean city (n = 1041; mean age = 77.7 years, 77.6% women). A comorbidity network analysis that estimates networks aggregated from measures of significant co-occurrence between pairs of diseases was employed to investigate comorbid associations between 31 chronic conditions. A cluster detection algorithm was employed to identify specific clusters of comorbidities. The association strength was expressed as the observed-to-expected ratio (OER). As a result, fifteen diseases were interconnected within the network (OER > 1, p-value <.05). While hypertension had a high prevalence, osteoporosis was the most central disease, co-occurring with numerous other diseases. The strongest associations among comorbidities were found between thyroid disease and urinary incontinence, chronic otitis media and osteoporosis, gastric duodenal ulcer/gastritis and anemia, and depression and gastric duodenal ulcer/gastritis (OER > 1.85). Three distinct clusters were identified as follows: (a) cataracts, osteoporosis, chronic otitis media, osteoarthritis/rheumatism, low back pain/sciatica, urinary incontinence, post-accident sequelae, and thyroid diseases; (b) hyperlipidemia, diabetes mellitus, and hypertension; and (c) depression, skin disease, gastric duodenal ulcer/gastritis, and anemia. The results may prove valuable in guiding the early diagnosis, management, and treatment of comorbidities in older adults living alone. © 2023, The Author(s), under exclusive licence to American Aging Association.
- DOI
- 10.1007/s11357-023-00987-z
- Appears in Collections:
- 의료원 > 의료원 > Journal papers
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