Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 송태진 | - |
dc.contributor.author | 김동엽 | - |
dc.date.accessioned | 2024-05-13T16:31:06Z | - |
dc.date.available | 2024-05-13T16:31:06Z | - |
dc.date.issued | 2024 | - |
dc.identifier.issn | 0002-9165 | - |
dc.identifier.other | OAK-35217 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/268137 | - |
dc.description.abstract | Background: Previous studies regarding BMI (kg/m2) and associated cardiovascular outcomes yield inconsistent results. Objectives: We aimed to investigate the association between body composition and cardiovascular outcomes according to BMI categories in the Korean general population. Methods: A total of 2,604,401 participants were enrolled in this nationwide cohort study using the National Health Insurance Service-Health Checkup data set. Predicted lean BMI (pLBMI), body fat mass index (pBFMI), and appendicular skeletal muscle mass index (pASMMI) were calculated using validated anthropometric prediction equations. A multivariable time-dependent Cox regression analysis was conducted to assess the association with cardiovascular outcomes. The results were presented with adjusted hazard ratios (HRs) with 95% confidence intervals (CIs), considering BMI categories (BMI < 18.5, BMI 18.5–24.9, BMI 25–29.9, and BMI ≥ 30). Results: Higher pLBMI and pASMMI were correlated with a reduced risk of composite cardiovascular outcomes. For pLBMI, HR was 0.910 (95% CI: 0.908, 0.913, P < 0.001) for males and 0.905 (95% CI: 0.899, 0.910, P < 0.001) for females. For pASMMI, HR was 0.825 (95% CI: 0.820, 0.829, P < 0.001) for males and 0.788 (95% CI: 0.777, 0.800, P < 0.001) for females. Conversely, a higher pBFMI was associated with an increased risk, with HR of 1.082 (95% CI: 1.071, 1.093, P < 0.001) for males and 1.181 (95% CI: 1.170, 1.192, P < 0.001) for females. Subgroup analysis based on BMI categories revealed no significant risk association for pBFMI in the BMI < 18.5 group. In the group with BMI ≥ 30, neither pLBMI nor pASMMI demonstrated a significant risk association. Conclusions: Our results highlight the value of pLBMI, pBFMI, and pASMMI as variables for assessing risk of composite cardiovascular outcomes. The significance of indicators may vary depending on BMI categories. © 2024 American Society for Nutrition | - |
dc.language | English | - |
dc.publisher | Elsevier B.V. | - |
dc.subject | BMI | - |
dc.subject | body composition | - |
dc.subject | cardiovascular outcome | - |
dc.subject | fat mass | - |
dc.subject | obesity | - |
dc.subject | skeletal muscle mass | - |
dc.title | Association of body composition indices with cardiovascular outcomes: a nationwide cohort study | - |
dc.type | Article | - |
dc.relation.issue | 4 | - |
dc.relation.volume | 119 | - |
dc.relation.index | SCIE | - |
dc.relation.index | SCOPUS | - |
dc.relation.startpage | 876 | - |
dc.relation.lastpage | 884 | - |
dc.relation.journaltitle | American Journal of Clinical Nutrition | - |
dc.identifier.doi | 10.1016/j.ajcnut.2024.02.015 | - |
dc.identifier.scopusid | 2-s2.0-85187561028 | - |
dc.author.google | Kim | - |
dc.author.google | Dongyeop | - |
dc.author.google | Hyung Jun | - |
dc.author.google | Song | - |
dc.author.google | Tae-Jin | - |
dc.contributor.scopusid | 송태진(55507164200) | - |
dc.contributor.scopusid | 김동엽(57192235701) | - |
dc.date.modifydate | 20240513132507 | - |