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Safety and efficacy of large-bore uncovered stents for treating malignant superior vena cava syndrome
- Title
- Safety and efficacy of large-bore uncovered stents for treating malignant superior vena cava syndrome
- Authors
- Lim Choi; Sang; Il Gwon; Dong; Ha Kim; Gun; Won Kim; Sung; Oh; Chang Hoon; Ko; Gi-Young
- Ewha Authors
- 오창훈
- SCOPUS Author ID
- 오창훈
- Issue Date
- 2024
- Journal Title
- European Journal of Radiology
- ISSN
- 0720-048X
- Citation
- European Journal of Radiology vol. 175
- Keywords
- Angioplasty; Endovascular procedure; Lung cancer; Stent; Superior vena cava syndrome
- Publisher
- Elsevier Ireland Ltd
- Indexed
- SCIE; SCOPUS
- Document Type
- Article
- Abstract
- Purpose: To investigate the safety and efficacy of large-bore uncovered stents for treating malignant superior vena cava syndrome. Methods: This retrospective study included 115 patients (89 men, 26 women; mean age 63.2 years; range 21–83 years) who underwent endovascular large-bore (≥18 mm in diameter) uncovered stent placement between August 2015 and July 2022. One patient was lost to follow-up. Therefore, 114 patients were available for follow-up. Results: Stent placement was technically successful in all 115 patients. Minor procedure-related complications occurred in nine (7.8 %) patients. One hundred eight (93.9 %) patients experienced complete or marked symptomatic relief (Kishi score ≤ 2) at a mean of 3 days after procedure. The cumulative stent patency rates were 98.2 %, 95 %, 93.7 %, 91.5 %, 83.5 %, and 83.5 % at 1, 3, 6, 12, 18, and 24 months, respectively. Stent occlusion occurred in ten (8.8 %) of 114 patients at a mean of 215 days (range 1–732 days) due to thrombosis (n = 7) and tumor ingrowth (n = 3). Stent occlusion did not occur in 21 patients who underwent subsequent central venous catheter insertion. The median patient survival time was 159 days (95 % confidence interval 102–216 days). Univariate and multivariate Cox regression analysis revealed adjuvant anticancer treatment (p = 0.001) and tumor response (p < 0.001) as independent predictors of patient survival. Conclusions: Endovascular placement of large-bore uncovered stents was a safe and effective treatment for malignant superior vena cava syndrome. Large-bore stent placement can effectively prevent stent occlusion by tumor ingrowth in most cases, and it can provide a sufficient diameter for subsequent insertion of central venous catheters. © 2024 Elsevier B.V.
- DOI
- 10.1016/j.ejrad.2024.111446
- Appears in Collections:
- 의료원 > 의료원 > Journal papers
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