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Predictors of in-hospital mortality after successful weaning of venoarterial extracorporeal membrane oxygenation in cardiogenic shock
- Title
- Predictors of in-hospital mortality after successful weaning of venoarterial extracorporeal membrane oxygenation in cardiogenic shock
- Authors
- Jeong; Joo Hee; Kook; Hyungdon; Lee; Seung Hun; Joo; Hyung Joon; Park; Jae Hyoung; Hong; Soon Jun; Kim; Mi-Na; Seong-Mi; Jung; Jae Seung; Yang; Jeong Hoon; Gwon; Hyeon-Cheol; Ahn; Chul-Min; Jang; Woo Jin; Hyun-Joong; Bae; Jang-Whan; Kwon; Sung Uk; Wang Soo; Jin-Ok; Sang-Don; Lim; Seong-Hoon; Yu; Cheol Woong
- Ewha Authors
- 장우진
- SCOPUS Author ID
- 장우진
- Issue Date
- 2023
- Journal Title
- Scientific Reports
- ISSN
- 2045-2322
- Citation
- Scientific Reports vol. 13, no. 1
- Publisher
- Nature Research
- Indexed
- SCIE; SCOPUS
- Document Type
- Article
- Abstract
- Limited knowledge exists regarding the predictors of mortality after successful weaning of venoarterial extracorporeal membrane oxygenation (ECMO). We aimed to identify predictors of in-hospital mortality in patients with cardiogenic shock (CS) after successful weaning from ECMO. Data were obtained from a multicenter registry of CS. Successful ECMO weaning was defined as survival with minimal mean arterial pressure (> 65 mmHg) for > 24 h after ECMO removal. The primary outcome was in-hospital mortality after successful ECMO weaning. Among 1247 patients with CS, 485 received ECMO, and 262 were successfully weaned from ECMO. In-hospital mortality occurred in 48 patients (18.3%). Survivors at discharge differed significantly from non-survivors in age, cardiovascular comorbidities, cause of CS, left ventricular ejection fraction, and use of adjunctive therapy. Five independent predictors for in-hospital mortality were identified: use of continuous renal replacement therapy (odds ratio 5.429, 95% confidence interval [CI] 2.468–11.940; p < 0.001), use of intra-aortic balloon pump (3.204, 1.105–9.287; p = 0.032), diabetes mellitus (3.152, 1.414–7.023; p = 0.005), age (1.050, 1.016–1.084; p = 0.003), and left ventricular ejection fraction after ECMO insertion (0.957, 0.927–0.987; p = 0.006). Even after successful weaning of ECMO, patients with irreversible risk factors should be recognized, and careful monitoring should be done for sign of deconditioning. © 2023, Springer Nature Limited.
- DOI
- 10.1038/s41598-023-44679-2
- Appears in Collections:
- 의료원 > 의료원 > Journal papers
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