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Pharmacogenomic Biomarkers and Their Applications in Psychiatry
- Title
- Pharmacogenomic Biomarkers and Their Applications in Psychiatry
- Authors
- Kam, Heejin; Jeong, Hotcherl
- Ewha Authors
- 정호철
- SCOPUS Author ID
- 정호철
- Issue Date
- 2020
- Journal Title
- GENES
- ISSN
- 2073-4425
- Citation
- GENES vol. 11, no. 12
- Keywords
- precision medicine; personalized medicine; pharmacogenomics; pharmacogenomic biomarkers; psychiatry; psychiatric disorders; epilepsy
- Publisher
- MDPI
- Indexed
- SCIE; SCOPUS
- Document Type
- Review
- Abstract
- Realizing the promise of precision medicine in psychiatry is a laudable and beneficial endeavor, since it should markedly reduce morbidity and mortality and, in effect, alleviate the economic and social burden of psychiatric disorders. This review aims to summarize important issues on pharmacogenomics in psychiatry that have laid the foundation towards personalized pharmacotherapy and, in a broader sense, precision medicine. We present major pharmacogenomic biomarkers and their applications in a variety of psychiatric disorders, such as depression, attention-deficit/hyperactivity disorder (ADHD), narcolepsy, schizophrenia, and bipolar disorder. In addition, we extend the scope into epilepsy, since antiepileptic drugs are widely used to treat psychiatric disorders, although epilepsy is conventionally considered to be a neurological disorder.
- DOI
- 10.3390/genes11121445
- Appears in Collections:
- 일반대학원 > 제약산업학과 > Journal papers
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