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Alginate, hyaluronic acid, and chitosan-based 3D printing hydrogel for cartilage tissue regeneration
- Title
- Alginate, hyaluronic acid, and chitosan-based 3D printing hydrogel for cartilage tissue regeneration
- Authors
- Jo Jang; Eun; Patel; Rajkumar; Sankpal; Narendra V.; Bouchard; Louis-S.; Madhumita
- Ewha Authors
- Madhumita Patel
- SCOPUS Author ID
- Madhumita Patel
- Issue Date
- 2024
- Journal Title
- European Polymer Journal
- ISSN
- 0014-3057
- Citation
- European Polymer Journal vol. 202
- Keywords
- 3D printing; Articular cartilage; Bioink; Cartilage tissue engineering; Polysaccharides
- Publisher
- Elsevier Ltd
- Indexed
- SCIE; SCOPUS
- Document Type
- Review
- Abstract
- The degradation of joint cartilage commonly characterizes osteoarthritis. Among the various therapeutic strategies, three-dimensional (3D) bioprinting has surfaced as an efficacious approach for fabricating cartilage tissue engineering (CTE) scaffolds. This technology enables the precise deposition of specific cell types, bioactive molecules, and structural matrices to construct 3D tissues. Central to bioprinting's effectiveness is bioink, which offers notable printability, biocompatibility, and tunable mechanical properties, essential for mimicking the native cartilage environment. Polysaccharide-based hydrogels, such as alginate, hyaluronic acid, and chitosan, are favored in this domain due to their cost-effectiveness, robust physicochemical properties, and biological functionality that emulate the extracellular matrix. This review discusses the critical role of these polysaccharide-based bioinks and their tailored modifications in advancing CTE applications. © 2023 Elsevier Ltd
- DOI
- 10.1016/j.eurpolymj.2023.112651
- Appears in Collections:
- 연구기관 > 나노바이오·에너지소재센터 > Journal papers
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