Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 이상은 | * |
dc.date.accessioned | 2024-02-06T16:30:04Z | - |
dc.date.available | 2024-02-06T16:30:04Z | - |
dc.date.issued | 2023 | * |
dc.identifier.issn | 1934-5925 | * |
dc.identifier.other | OAK-34637 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/266953 | - |
dc.description.abstract | Background: Non-obstructing small coronary plaques may not be well recognized by expert readers during coronary computed tomography angiography (CCTA) evaluation. Recent developments in atherosclerosis imaging quantitative computed tomography (AI-QCT) enabled by machine learning allow for whole-heart coronary phenotyping of atherosclerosis, but its diagnostic role for detection of small plaques on CCTA is unknown.Methods: We performed AI-QCT in patients who underwent serial CCTA in the multinational PARADIGM study. AI-QCT results were verified by a level III experienced reader, who was blinded to baseline and follow-up status of CCTA. This retrospective analysis aimed to characterize small plaques on baseline CCTA and evaluate their serial changes on follow-up imaging. Small plaques were defined as a total plaque volume <50 mm (3) .Results: A total of 99 patients with 502 small plaques were included. The median total plaque volume was 6.8 mm (3) (IQR 3.5-13.9 mm (3) ), most of which was non-calcified (median 6.2 mm (3) ; 2.9-12.3 mm (3) ). The median age at the time of baseline CCTA was 61 years old and 63% were male. The mean interscan period was 3.8 +/- 1.6 years. On follow-up CCTA, 437 (87%) plaques were present at the same location as small plaques on baseline CCTA; 72% were larger and 15% decreased in volume. The median total plaque volume and non-calcified plaque volume increased to 18.9 mm (3) (IQR 8.3-45.2 mm (3) ) and 13.8 mm (3) (IQR 5.7-33.4 mm (3) ), respectively, among plaques that persisted on follow-up CCTA. Small plaques no longer visualized on follow-up CCTA were significantly more likely to be of lower volume, shorter in length, non-calcified, and more distal in the coronary artery, as compared with plaques that persisted at follow-up.Conclusion: In this retrospective analysis from the PARADIGM study, small plaques (<50 mm (3) ) identified by AI-QCT persisted at the same location and were often larger on follow-up CCTA. | * |
dc.language | English | * |
dc.publisher | ELSEVIER SCIENCE INC | * |
dc.subject | Coronary CT angiography | * |
dc.subject | Arti ficial intelligence | * |
dc.subject | Small plaque | * |
dc.subject | Atherosclerosis | * |
dc.subject | Coronary | * |
dc.title | How early can atherosclerosis be detected by coronary CT angiography? Insights from quantitative CT analysis of serial scans in the PARADIGM trial | * |
dc.type | Article | * |
dc.relation.issue | 6 | * |
dc.relation.volume | 17 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 407 | * |
dc.relation.lastpage | 412 | * |
dc.relation.journaltitle | JOURNAL OF CARDIOVASCULAR COMPUTED TOMOGRAPHY | * |
dc.identifier.doi | 10.1016/j.jcct.2023.08.012|http://dx.doi.org/10.1016/j.jcct.2023.08.012 | * |
dc.identifier.wosid | WOS:001141777000001 | * |
dc.identifier.scopusid | 2-s2.0-85173136815 | * |
dc.author.google | Cardoso, Rhanderson | * |
dc.author.google | Choi, Andrew D. | * |
dc.author.google | Shiyovich, Arthur | * |
dc.author.google | Besser, Stephanie A. | * |
dc.author.google | Min, James K. | * |
dc.author.google | Earls, James | * |
dc.author.google | Andreini, Daniele | * |
dc.author.google | Al-Mallah, Mouaz H. | * |
dc.author.google | Budoff, Matthew J. | * |
dc.author.google | Cademartiri, Filippo | * |
dc.author.google | Chinnaiyan, Kavitha | * |
dc.author.google | Choi, Jung Hyun | * |
dc.author.google | Chun, Eun Ju | * |
dc.author.google | Conte, Edoardo | * |
dc.author.google | Gottlieb, Ilan | * |
dc.author.google | Hadamitzky, Martin | * |
dc.author.google | Kim, Yong-Jin | * |
dc.author.google | Lee, Byoung Kwon | * |
dc.author.google | Leipsic, Jonathon A. | * |
dc.author.google | Maffei, Erica | * |
dc.author.google | Marques, Hugo | * |
dc.author.google | Goncalves, Pedro de Araujo | * |
dc.author.google | Pontone, Gianluca | * |
dc.author.google | Lee, Sang-Eun | * |
dc.author.google | Sung, Ji Min | * |
dc.author.google | Virmani, Renu | * |
dc.author.google | Samady, Habib | * |
dc.author.google | Lin, Fay Y. | * |
dc.author.google | Stone, Peter H. | * |
dc.author.google | Berman, Daniel S. | * |
dc.author.google | Narula, Jagat | * |
dc.author.google | Shaw, Leslee J. | * |
dc.author.google | Bax, Jeroen J. | * |
dc.author.google | Chang, Hyuk-Jae | * |
dc.author.google | Blankstein, Ron | * |
dc.contributor.scopusid | 이상은(57213176330) | * |
dc.date.modifydate | 20240502144901 | * |