Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 최윤희 | * |
dc.contributor.author | 이덕희 | * |
dc.contributor.author | 김건 | * |
dc.date.accessioned | 2023-10-27T16:30:03Z | - |
dc.date.available | 2023-10-27T16:30:03Z | - |
dc.date.issued | 2023 | * |
dc.identifier.issn | 2112-1265 | * |
dc.identifier.other | OAK-34061 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/266471 | - |
dc.description.abstract | Background: Acute gastrointestinal bleeding (GI bleeding) can range from mild symptoms to life-threatening conditions that require emergency intervention. Therefore, it is important to first identify the high-risk and low-risk patients in the emergency department (ED). Aims: This study aimed to investigate the usefulness of a three-hourly interval for determining the lactate clearance, which is shorter than the time interval in previous studies, in order to predict the prognosis early in patients with GI bleeding. Methods: This retrospective study involved patients who visited for complaining of GI bleeding symptoms. Initial lactate levels were measured upon arrival at the ED and measured again 3 h later after performing initial resuscitation. And 3-h lactate clearance was calculated. Lactate and 3-h lactate clearance for predicting outcomes were evaluated by the area under the receiver operating characteristic (AUROC) curve. Results: A total of 104 patients were enrolled and 21 patients (20.2%) died in the hospital. Multivariate logistic regression showed that 3-h lactate clearance was a significant predictor of in-hospital mortality. The AUROC of 3-h lactate clearance for predicting in-hospital mortality was 0.756. The sensitivity and specificity were 66.67% and 75.90%. On combining lactate clearance, total bilirubin, and PTT, the AUROC was 0.899 for predicting in-hospital mortality. Conclusions: This study validated that lactate clearance at three-hourly intervals is useful for early prediction of mortality and prognosis in patients with GI bleeding. It is important to perform not only an initial lactate measurement, but also a follow-up lactate measurement after initial resuscitation to check the lactate clearance. © 2022, The Author(s), under exclusive licence to Royal Academy of Medicine in Ireland. | * |
dc.language | English | * |
dc.publisher | Springer Science and Business Media Deutschland GmbH | * |
dc.subject | Emergency department | * |
dc.subject | Gastrointestinal hemorrhage | * |
dc.subject | In-hospital mortality | * |
dc.subject | Lactate | * |
dc.title | Early lactate clearance for predicting outcomes in patients with gastrointestinal bleeding | * |
dc.type | Article | * |
dc.relation.issue | 4 | * |
dc.relation.volume | 192 | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 1923 | * |
dc.relation.lastpage | 1929 | * |
dc.relation.journaltitle | Irish Journal of Medical Science | * |
dc.identifier.doi | 10.1007/s11845-022-03185-6 | * |
dc.identifier.scopusid | 2-s2.0-85139779190 | * |
dc.author.google | Kim K. | * |
dc.author.google | Lee D.H. | * |
dc.author.google | Choi Y.H. | * |
dc.author.google | Bae S.J. | * |
dc.contributor.scopusid | 최윤희(57190749692;58492359100) | * |
dc.contributor.scopusid | 이덕희(55698960700) | * |
dc.contributor.scopusid | 김건(57199091586) | * |
dc.date.modifydate | 20240304124402 | * |