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Efficacy of scrambler therapy in patients with painful diabetic peripheral neuropathy: A single-arm, prospective, pilot study
- Title
- Efficacy of scrambler therapy in patients with painful diabetic peripheral neuropathy: A single-arm, prospective, pilot study
- Authors
- Yoo; Seung Hee; Kim; Won-Joong; Chae; Ji Seon; Kang; Bo Kyung; Min Jeong; Beak; Min Hyouk
- Ewha Authors
- 김원중; 강민정; 유승희; 채지선
- SCOPUS Author ID
- 김원중; 강민정; 유승희; 채지선
- Issue Date
- 2023
- Journal Title
- Medicine (United States)
- ISSN
- 0025-7974
- Citation
- Medicine (United States) vol. 102, no. 39, pp. E35357
- Keywords
- chronic pains; diabetes mellitus; neuropathic pain; painful diabetic neuropathy; percutaneous neuromodulation therapy; visual analog scale
- Publisher
- Lippincott Williams and Wilkins
- Indexed
- SCIE; SCOPUS
- Document Type
- Article
- Abstract
- Background: A variety of medications are available to manage painful diabetic peripheral neuropathy (DPN), but the proper treatment remains challenging. Accordingly, various neuromodulation modalities have been used. However, no prospective clinical trials have evaluated the use of scrambler therapy (ST) in painful DPN. This study aimed to explore the long-term effects of ST in managing painful DPN. Methods: The patients received 10 consecutive STs of 45 minutes every 1 to 2 days. The primary outcome was pain score. We measured the visual analog scale (VAS) pain scores at baseline, during ST, immediately after ST, and at 1, 2, 3, and 6 months after ST. The secondary outcomes were Michigan Neuropathy Screening Instrument (MNSI), Semmes-Weinstein monofilament test, and Leeds Assessment of Neuropathic Symptoms and Signs pain scores, which were measured at baseline, immediately after ST, and at 1, 2, 3, and 6 months after ST. Results: VAS scores showed significant improvement at the 8th, 9th, and 10th sessions during ST and 1 month after ST. The MNSI self-report component score was decreased 1 month after the ST. However, all other outcomes did not show significant differences compared to the baseline. Conclusion: ST may have short-term effects and limited long-term effects on painful DPN. © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.
- DOI
- 10.1097/MD.0000000000035357
- Appears in Collections:
- 의과대학 > 의학과 > Journal papers
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