Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 주계일 | * |
dc.date.accessioned | 2023-07-31T16:31:21Z | - |
dc.date.available | 2023-07-31T16:31:21Z | - |
dc.date.issued | 2023 | * |
dc.identifier.issn | 1448-8617 | * |
dc.identifier.other | OAK-33463 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/265380 | - |
dc.description.abstract | While the natural carbohydrate alginate has enabled effective three-dimensional (3D) extrusion bioprinting, it still suffers from some issues such as low printability and resolution and limited cellular function due to ionic crosslinking dependency. Here, we prepared a harmless visible light-based photocrosslinkable alginate by chemically bonding tyrosine-like residues onto alginate chains to propose a new microgel manufacturing system for the development of 3D-printed bioinks. The photocrosslinkable tyramine-conjugated alginate microgel achieved both higher cell viability and printing resolution compared to the bulk gel form. This alginate-based jammed granular microgel bioink showed excellent 3D bioprinting ability with maintained structural stability. As a biocompatible material, the developed multiple cell-loaded photocrosslinkable alginate-based microgel bioink provided excellent proliferation and migration abilities of laden living cells, providing an effective strategy to construct implantable functional artificial organ structures for 3D bioprinting-based tissue engineering. © 2023 Elsevier Ltd | * |
dc.language | English | * |
dc.publisher | Elsevier Ltd | * |
dc.subject | 3D printing bioink | * |
dc.subject | Jammed microgels | * |
dc.subject | Multiple cell-laden structures | * |
dc.subject | Photocrosslinkable alginate | * |
dc.subject | Tyramine-conjugated alginate | * |
dc.title | Visible light-crosslinkable tyramine-conjugated alginate-based microgel bioink for multiple cell-laden 3D artificial organ | * |
dc.type | Article | * |
dc.relation.volume | 313 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.journaltitle | Carbohydrate Polymers | * |
dc.identifier.doi | 10.1016/j.carbpol.2023.120895 | * |
dc.identifier.wosid | WOS:000983634400001 | * |
dc.identifier.scopusid | 2-s2.0-85152460951 | * |
dc.author.google | Lee S. | * |
dc.author.google | Choi G. | * |
dc.author.google | Yang Y.J. | * |
dc.author.google | Joo K.I. | * |
dc.author.google | Cha H.J. | * |
dc.contributor.scopusid | 주계일(21739452800) | * |
dc.date.modifydate | 20240322131109 | * |