Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 박시재 | * |
dc.date.accessioned | 2023-07-31T16:31:14Z | - |
dc.date.available | 2023-07-31T16:31:14Z | - |
dc.date.issued | 2023 | * |
dc.identifier.issn | 1226-086X | * |
dc.identifier.other | OAK-33525 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/265333 | - |
dc.description.abstract | M3HB (Methyl 3-hydroxybutyrate), known as an alternative energy source for cells with impaired metabolic function, has recently been reported to have therapeutic effects on Alzheimer's disease and inhibition of apoptosis. In this study, the enzymatic conversion of M3HB from methanol and beta-hydroxybutyric acid (BHB) by lipase-catalyzed esterification was performed for the first time. The reaction conditions for maximum M3HB conversion were as follows: Novozym 435, 15 g/L; BHB:methanol molar ratio, 1:2; reaction temperature, 40 °C; and organic solvent, chloroform. The lipase-based M3HB synthesis achieved about 94.6% conversion through a step-by-step optimization, and is expected to contribute to future bioindustry applications. © 2023 The Korean Society of Industrial and Engineering Chemistry | * |
dc.language | English | * |
dc.publisher | Korean Society of Industrial Engineering Chemistry | * |
dc.subject | Beta-hydroxybutyric acid (PubChem CID: 441) | * |
dc.subject | Enzymatic esterification | * |
dc.subject | Lipase | * |
dc.subject | Methanol (PubChem CID: 887) | * |
dc.subject | Methyl 3-hydroxybutyrate | * |
dc.subject | Methyl 3-hydroxybutyrate (PubChem CID: 15146) | * |
dc.subject | β-hydroxybutyric acid | * |
dc.title | Novel synthetic pathway for methyl 3-hydroxybutyrate from β-hydroxybutyric acid and methanol by enzymatic esterification | * |
dc.type | Article | * |
dc.relation.volume | 123 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.index | KCI | * |
dc.relation.startpage | 355 | * |
dc.relation.lastpage | 360 | * |
dc.relation.journaltitle | Journal of Industrial and Engineering Chemistry | * |
dc.identifier.doi | 10.1016/j.jiec.2023.03.052 | * |
dc.identifier.wosid | WOS:000993063700001 | * |
dc.identifier.scopusid | 2-s2.0-85152648535 | * |
dc.author.google | Son J. | * |
dc.author.google | Lee H. | * |
dc.author.google | Lee T. | * |
dc.author.google | Sohn H. | * |
dc.author.google | Jae Park S. | * |
dc.author.google | Na J.-G. | * |
dc.author.google | Woo Seo S. | * |
dc.author.google | Wook Lee J. | * |
dc.author.google | Young Yoo H. | * |
dc.author.google | Park C. | * |
dc.contributor.scopusid | 박시재(57191670770) | * |
dc.date.modifydate | 20240322131024 | * |