Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 장우진 | * |
dc.date.accessioned | 2023-07-31T16:31:08Z | - |
dc.date.available | 2023-07-31T16:31:08Z | - |
dc.date.issued | 2023 | * |
dc.identifier.issn | 2047-9980 | * |
dc.identifier.other | OAK-33588 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/265288 | - |
dc.description.abstract | BACKGROUND: Despite the benefit of culprit-only percutaneous coronary intervention (PCI) in the CULPRIT-SHOCK (Culprit Lesion Only PCI Versus Multi-vessel PCI in Cardiogenic Shock) trial, the optimal revascularization strategy for refractory car-diogenic shock (CS) requiring mechanical circulatory support devices remains controversial. This study aimed to compare clinical outcomes between the culprit-only and immediate multivessel PCI strategies in patients with acute myocardial infarction complicated by CS who underwent venoarterial-extracorporeal membrane oxygenation before revascularization. METHODS AND RESULTS: This study included patient-pooled data from the RESCUE (Retrospective and Prospective Observational Study to Investigate Clinical Outcomes and Efficacy of Left Ventricular Assist Devices for Korean Patients With Cardiogenic Shock) and SMC-ECMO (Samsung Medical Center– Extracorporeal Membrane Oxygenation) registries. A total of 315 patients with acute myocardial infarction with multivessel disease who underwent venoarterial-extracorporeal membrane oxygenation before revascularization attributable to refractory CS were included in this analysis. The study population was classified into culprit-only versus immediate multivessel PCI according to nonculprit lesion treatment strategies. The primary end point was 30-day mortality or renal-replacement therapy, and the key secondary end point was 12-month follow-up mortality. Among the study population, 175 (55.6%) underwent culprit-only PCI and 140 (44.4%) underwent immediate multivessel PCI. Compared with culprit-only PCI, immediate multivessel PCI was associated with significantly lower risks of 30-day mortality or renal-replacement therapy (68.0% versus 54.3%; P=0.018) and all-cause mortality during 12 months of follow-up (59.5% versus 47.5%; hazard ratio [HR], 0.689 [95% CI, 0.506– 0.939]; P=0.018) in patients with acute myocardial infarction and CS who underwent venoarterial-extracorporeal membrane oxygenation before revascularization. These results were also consistent in the 99 pairs of propensity score– matched population (60.6% versus 43.6%; HR, 0.622 [95% CI, 0.420– 0.922]; P=0.018). CONCLUSIONS: Among patients with acute myocardial infarction with multivessel disease complicated by advanced CS requiring venoarterial-extracorporeal membrane oxygenation before revascularization, immediate multivessel PCI was associated with lower incidences of 30-day mortality or renal replacement therapy and 12-month follow-up mortality, compared with culprit-only PCI. REGISTRATION INFORMATION: clinicaltrials.gov. Identifier: NCT02985008. © 2023 The Authors. | * |
dc.language | English | * |
dc.publisher | American Heart Association Inc. | * |
dc.subject | acute myocardial infarction | * |
dc.subject | cardiogenic shock | * |
dc.subject | culprit | * |
dc.subject | multivessel disease | * |
dc.subject | percutaneous coronary intervention | * |
dc.title | Culprit-Only Versus Immediate Multivessel Percutaneous Coronary Intervention in Patients With Acute Myocardial Infarction Complicating Advanced Cardiogenic Shock Requiring Venoarterial-Extracorporeal Membrane Oxygenation | * |
dc.type | Article | * |
dc.relation.issue | 10 | * |
dc.relation.volume | 12 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.journaltitle | Journal of the American Heart Association | * |
dc.identifier.doi | 10.1161/JAHA.123.029792 | * |
dc.identifier.wosid | WOS:001003633600034 | * |
dc.identifier.scopusid | 2-s2.0-85159740597 | * |
dc.author.google | Choi K.H. | * |
dc.author.google | Yang J.H. | * |
dc.author.google | Park T.K. | * |
dc.author.google | Lee J.M. | * |
dc.author.google | Song Y.B. | * |
dc.author.google | Hahn J.-Y. | * |
dc.author.google | Choi S.-H. | * |
dc.author.google | Ahn C.-M. | * |
dc.author.google | Yu C.W. | * |
dc.author.google | Park I.H. | * |
dc.author.google | Jang W.J. | * |
dc.author.google | Kim H.-J. | * |
dc.author.google | Bae J.-W. | * |
dc.author.google | Kwon S.U. | * |
dc.author.google | Lee H.-J. | * |
dc.author.google | Lee W.S. | * |
dc.author.google | Jeong J.-O. | * |
dc.author.google | Park S.-D. | * |
dc.author.google | Kang T.-S. | * |
dc.author.google | Gwon H.-C. | * |
dc.contributor.scopusid | 장우진(57212421225;56522417800) | * |
dc.date.modifydate | 20240426132658 | * |