Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이정경 | * |
dc.contributor.author | 문영철 | * |
dc.contributor.author | 김진실 | * |
dc.contributor.author | 이효정 | * |
dc.date.accessioned | 2023-04-18T16:31:04Z | - |
dc.date.available | 2023-04-18T16:31:04Z | - |
dc.date.issued | 2023 | * |
dc.identifier.issn | 0284-1851 | * |
dc.identifier.other | OAK-33280 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/265005 | - |
dc.description.abstract | Background: Patients with underlying hematologic malignancy have a higher risk of developing systemic amyloidosis, which worsens their prognosis. Histopathologic detection of amyloid deposits in tissue biopsy specimens is the only diagnostic method for amyloidosis. Purpose: To compare the efficacy of ultrasound-guided percutaneous core needle biopsy (USPCB) of abdominal subcutaneous fat with that of bone marrow biopsy (BMB) for diagnosing amyloidosis. Material and Methods: A total of 90 consecutive patients with underlying hematologic disorders who underwent both USPCB of abdominal subcutaneous fat and BMB for suspicion of amyloid deposition during a 10-year period were included in this retrospective study. Results: The sensitivity and specificity of detecting amyloid deposition were 85.7% and 100%, respectively, with USPCB as opposed to 4.8% and 100%, respectively, with BMB, and the sensitivity was significantly higher with USPCB (P < 0.001). The mean number of times USPCB was performed was 3.3. There were no major complications associated with USPCB. The sensitivity of detecting amyloidosis was not different between the 18-G needle group and the 14-G group (100% vs. 80%; P = 0.623). Logistic regression analysis revealed that acquiring more cores from USPCB and thinner fat tissues were statistically significant factors that affected the diagnostic accuracy of USPCB for amyloid detection. Conclusion: The sensitivity of amyloid deposition was significantly higher with USPCB of abdominal subcutaneous fat than BMB. Acquiring more cores by multiple biopsies instead of using a larger bore needle and thin subcutaneous fat pad may be a favorable factor for the diagnostic accuracy of USPCB. © The Foundation Acta Radiologica 2023. | * |
dc.language | English | * |
dc.publisher | SAGE Publications Inc. | * |
dc.subject | abdominal subcutaneous fat | * |
dc.subject | Amyloidosis | * |
dc.subject | biopsy | * |
dc.subject | bone marrow examination | * |
dc.subject | ultrasound | * |
dc.title | Ultrasound-guided percutaneous core needle biopsy of abdominal subcutaneous fat for diagnosing amyloidosis: comparison with bone marrow biopsy | * |
dc.type | Article | * |
dc.relation.issue | 5 | * |
dc.relation.volume | 64 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 1770 | * |
dc.relation.lastpage | 1774 | * |
dc.relation.journaltitle | Acta Radiologica | * |
dc.identifier.doi | 10.1177/02841851231151369 | * |
dc.identifier.wosid | WOS:000928552300001 | * |
dc.identifier.scopusid | 2-s2.0-85147668501 | * |
dc.author.google | Lee H.J. | * |
dc.author.google | Kim J.S. | * |
dc.author.google | Mun Y.-C. | * |
dc.author.google | Lee J.K. | * |
dc.contributor.scopusid | 이정경(35316081600) | * |
dc.contributor.scopusid | 문영철(7003363716) | * |
dc.contributor.scopusid | 김진실(57189764787) | * |
dc.contributor.scopusid | 이효정(57209160649) | * |
dc.date.modifydate | 20240422115947 | * |