Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 장우진 | * |
dc.date.accessioned | 2023-04-18T16:30:06Z | - |
dc.date.available | 2023-04-18T16:30:06Z | - |
dc.identifier.issn | 0028-4793 | * |
dc.identifier.issn | 1533-4406 | * |
dc.identifier.other | OAK-33313 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/264976 | - |
dc.description.abstract | BACKGROUNDData regarding clinical outcomes after intravascular imaging-guided percutaneous coronary intervention (PCI) for complex coronary-artery lesions, as compared with outcomes after angiography-guided PCI, are limited. METHODSIn this prospective, multicenter, open-label trial in South Korea, we randomly assigned patients with complex coronary-artery lesions in a 2:1 ratio to undergo either intravascular imaging-guided PCI or angiography-guided PCI. In the intra-vascular imaging group, the choice between intravascular ultrasonography and optical coherence tomography was at the operators' discretion. The primary end point was a composite of death from cardiac causes, target-vessel-related myocardial infarction, or clinically driven target-vessel revascularization. Safety was also assessed. RESULTSA total of 1639 patients underwent randomization, with 1092 assigned to undergo intravascular imaging-guided PCI and 547 assigned to undergo angiography-guided PCI. At a median follow-up of 2.1 years (interquartile range, 1.4 to 3.0), a primary end-point event had occurred in 76 patients (cumulative incidence, 7.7%) in the intravascular imaging group and in 60 patients (cumulative incidence, 12.3%) in the angiography group (hazard ratio, 0.64; 95% confidence interval, 0.45 to 0.89; P = 0.008). Death from cardiac causes occurred in 16 patients (cumulative incidence, 1.7%) in the intravascular imaging group and in 17 patients (cumulative incidence, 3.8%) in the angiography group; target-vessel-related myocardial in-farction occurred in 38 (cumulative incidence, 3.7%) and 30 (cumulative incidence, 5.6%), respectively; and clinically driven target-vessel revascularization in 32 (cumulative incidence, 3.4%) and 25 (cumulative incidence, 5.5%), respectively. There were no apparent between-group differences in the incidence of procedure-related safety events. CONCLUSIONSAmong patients with complex coronary-artery lesions, intravascular imaging- guided PCI led to a lower risk of a composite of death from cardiac causes, target-vessel-related myocardial infarction, or clinically driven target-vessel revascularization than angiography-guided PCI. (Supported by Abbott Vascular and Boston Scientific; RENOVATE-COMPLEX-PCI ClinicalTrials.gov number, NCT03381872). | * |
dc.language | English | * |
dc.publisher | MASSACHUSETTS MEDICAL SOC | * |
dc.title | Intravascular Imaging-Guided or Angiography-Guided Complex PCI | * |
dc.type | Article | * |
dc.type | Early Access | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.journaltitle | NEW ENGLAND JOURNAL OF MEDICINE | * |
dc.identifier.doi | 10.1056/NEJMoa2216607 | * |
dc.identifier.wosid | WOS:000943609600001 | * |
dc.author.google | Lee, Joo Myung | * |
dc.author.google | Choi, Ki Hong | * |
dc.author.google | Song, Young Bin | * |
dc.author.google | Lee, Jong-Young | * |
dc.author.google | Lee, Seung-Jae | * |
dc.author.google | Lee, Sang Yeub | * |
dc.author.google | Kim, Sang Min | * |
dc.author.google | Yun, Kyeong Ho | * |
dc.author.google | Cho, Jae Young | * |
dc.author.google | Kim, Chan Joon | * |
dc.author.google | Ahn, Hyo-Suk | * |
dc.author.google | Nam, Chang-Wook | * |
dc.author.google | Yoon, Hyuck-Jun | * |
dc.author.google | Park, Yong Hwan | * |
dc.author.google | Lee, Wang Soo | * |
dc.author.google | Jeong, Jin-Ok | * |
dc.author.google | Song, Pil Sang | * |
dc.author.google | Doh, Joon-Hyung | * |
dc.author.google | Jo, Sang-Ho | * |
dc.author.google | Yoon, Chang-Hwan | * |
dc.author.google | Kang, Min Gyu | * |
dc.author.google | Koh, Jin-Sin | * |
dc.author.google | Lee, Kwan Yong | * |
dc.author.google | Lim, Young-Hyo | * |
dc.author.google | Cho, Yun-Hyeong | * |
dc.author.google | Cho, Jin-Man | * |
dc.author.google | Jang, Woo Jin | * |
dc.author.google | Chun, Kook-Jin | * |
dc.author.google | Hong, David | * |
dc.author.google | Park, Taek Kyu | * |
dc.author.google | Yang, Jeong Hoon | * |
dc.author.google | Choi, Seung-Hyuk | * |
dc.author.google | Gwon, Hyeon-Cheol | * |
dc.author.google | Hahn, Joo-Yong | * |
dc.contributor.scopusid | 장우진(57212421225;56522417800) | * |
dc.date.modifydate | 20240426132658 | * |