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First-Pass Recanalization with EmboTrap II in Acute Ischemic Stroke (FREE-AIS): A Multicenter Prospective Study
- Title
- First-Pass Recanalization with EmboTrap II in Acute Ischemic Stroke (FREE-AIS): A Multicenter Prospective Study
- Authors
- Baek, Jang-Hyun; Kim, Byung Moon; Suh, Sang Hyun; Jeon, Hong -Jun; Ihm, Eun Hyun; Park, Hyungjong; Kim, Chang-Hyun; Cha, Sang-Hoon; Choi, Chi-Hoon; Yi, Kyung Sik; Kim, Jun-Hwee; Suh, Sangil; Kim, Byungjun; Chang, Yoonkyung; Kim, So Yeon; Oh, Jae Sang; Heo, Ji Hoe; Kim, Dong Joon; Nam, Hyo Suk; Kim, Young Dae
- Ewha Authors
- 장윤경
- SCOPUS Author ID
- 장윤경
- Issue Date
- 2023
- Journal Title
- KOREAN JOURNAL OF RADIOLOGY
- ISSN
- 1229-6929
2005-8330
- Citation
- KOREAN JOURNAL OF RADIOLOGY vol. 24, no. 2, pp. 145 - 154
- Keywords
- First-pass recanalization; Thrombectomy; Stent; Stroke
- Publisher
- KOREAN SOCIETY OF RADIOLOGY
- Indexed
- SCIE; SCOPUS; KCI
- Document Type
- Article
- Abstract
- Objective: We aimed to evaluate the efficacy of EmboTrap II in terms of first-pass recanalization and to determine whether it could yield favorable outcomes.Materials and Methods: In this multicenter, prospective study, we consecutively enrolled patients who underwent mechanical thrombectomy using EmboTrap II as a front-line device. The primary outcome was the first pass effect (FPE) rate defined by modified Thrombolysis In Cerebral Infarction (mTICI) grade 2c or 3 by the first pass of EmboTrap II. In addition, modified FPE (mFPE; mTICI grade 2b-3 by the first pass of EmboTrap II), successful recanalization (final mTICI grade 2b-3), and clinical outcomes were assessed. We also analyzed the effect of FPE on a modified Rankin Scale (mRS) score of 0-2 at 3 months.Results: Two hundred-ten patients (mean age +/- standard deviation, 73.3 +/- 11.4 years; male, 55.7%) were included. Ninetynine patients (47.1%) had FPE, and mFPE was achieved in 150 (71.4%) patients. Successful recanalization was achieved in 191 (91.0%) patients. Among them, 164 (85.9%) patients underwent successful recanalization by exclusively using EmboTrap II. The time from groin puncture to FPE was 25.0 minutes (interquartile range, 17.0-35.0 minutes). Procedure-related complications were observed in seven (3.3%) patients. Symptomatic intracranial hemorrhage developed in 14 (6.7%) patients. One hundred twenty-three (58.9% of 209 completely followed) patients had an mRS score of 0-2. Sixteen (7.7% of 209) patients died during the follow-up period. Patients who had successful recanalization with FPE were four times more likely to have an mRS score of 0-2 than those who had successful recanalization without FPE (adjusted odds ratio, 4.13; 95% confidence interval, 1.59-10.8; p = 0.004).Conclusion: Mechanical thrombectomy using the front-line EmboTrap II is effective and safe. In particular, FPE rates were high. Achieving FPE was important for an mRS score of 0-2, even in patients with successful recanalization.
- DOI
- 10.3348/kjr.2022.0618
- Appears in Collections:
- 의과대학 > 의학과 > Journal papers
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