Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김명수 | * |
dc.date.accessioned | 2023-02-17T16:30:08Z | - |
dc.date.available | 2023-02-17T16:30:08Z | - |
dc.date.issued | 2022 | * |
dc.identifier.issn | 2466-0493 | * |
dc.identifier.issn | 2466-054X | * |
dc.identifier.other | OAK-32924 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/263959 | - |
dc.description.abstract | Purpose: To assess the effect of ciprofloxacin (CP) and fosfomycin compared with CP and amikacin in patients with a fluoroquino-lone (FQ)-resistant rectal flora who have undergone transrectal ultrasound-guided prostate biopsy (TRUSPB).Materials and Methods: In total, 516 patients with FQ-resistant rectal flora based on rectal swab cultures were divided into two groups according to prophylactic antibiotics. Patients in both groups were administered CP (400 mg, intravenous [IV], twice daily) on the same day as TRUSPB and 1 day after biopsy. The amikacin group (n=260) was administered a single injection of amikacin (1 g, IV) 1 hour before TRUSPB, whereas the fosfomycin group (n=256) was administered fosfomycin (3 g, orally) the night before the procedure. The primary endpoint was the rate of infectious complications in the two groups. Results: Overall, 13 patients (2.5%) reported infectious complications: 12 patients (4.62%) in the amikacin group compared with 1 patient (0.39%) in the fosfomycin group (risk ratio, 0.09; 95% confidence interval [CI], 0.01-0.65), respectively, which was a statisti-cally significant difference (p=0.017). This corresponds to a number needed to treat of 24 patients (95% CI, 15-65) to prevent one infectious complication. In the multivariate analysis to assess variables related to infectious complications, prophylactic antibiotics with added fosfomycin was associated with infectious complications (odds ratio, 0.060; 95% CI, 0.008-0.459).Conclusions: In the era of FQ resistance, CP and fosfomycin may reduce the rate of infectious complications compared with CP and amikacin prophylaxis. | * |
dc.language | English | * |
dc.publisher | KOREAN UROLOGICAL ASSOC | * |
dc.subject | Antibiotic prophylaxis | * |
dc.subject | Biopsy | * |
dc.subject | Ciprofloxacin | * |
dc.subject | Fosfomycin | * |
dc.subject | Prostate | * |
dc.title | Comparison of amikacin with fosfomycin as an add-on to ciprofloxacin for antibiotic prophylaxis in transrectal prostate biopsy: A single-center retrospective study | * |
dc.type | Article | * |
dc.relation.issue | 6 | * |
dc.relation.volume | 63 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.index | KCI | * |
dc.relation.startpage | 663 | * |
dc.relation.lastpage | 670 | * |
dc.relation.journaltitle | INVESTIGATIVE AND CLINICAL UROLOGY | * |
dc.identifier.doi | 10.4111/icu.20220147 | * |
dc.identifier.wosid | WOS:000907887700010 | * |
dc.author.google | Yu, Seong Hyeon | * |
dc.author.google | Jung, Seung, II | * |
dc.author.google | Ryu, Ji Won | * |
dc.author.google | Kim, Myung Soo | * |
dc.author.google | Chung, Ho Seok | * |
dc.author.google | Hwang, Eu Chang | * |
dc.author.google | Kwon, Dong Deuk | * |
dc.contributor.scopusid | 김명수(57199747517) | * |
dc.date.modifydate | 20240311140527 | * |