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Oral Health and Risk of Retinal Vascular Occlusions: A Nationwide Cohort Study
- Title
- Oral Health and Risk of Retinal Vascular Occlusions: A Nationwide Cohort Study
- Authors
- Chang, Yoonkyung; Kim, Sung-Hee; Jeon, Jimin; Song, Tae-Jin; Kim, Jinkwon
- Ewha Authors
- 송태진; 장윤경; 김성희
- SCOPUS Author ID
- 송태진; 장윤경; 김성희
- Issue Date
- 2023
- Journal Title
- JOURNAL OF PERSONALIZED MEDICINE
- ISSN
- 2075-4426
- Citation
- JOURNAL OF PERSONALIZED MEDICINE vol. 13, no. 1
- Keywords
- periodontitis; tooth brushing; oral health; retinal vascular occlusion
- Publisher
- MDPI
- Indexed
- SCIE; SCOPUS
- Document Type
- Article
- Abstract
- Retinal vascular occlusions are a common cause of visual loss. The association between oral health and the risk of retinal vascular occlusions remains unknown. We investigated whether oral health was associated with the risk of retinal vascular occlusions. We conducted a retrospective cohort study including 138,484 participants who completed a national health screening program with an oral health examination from the National Health Insurance Service-National Health Screening Cohort (NHIS-HEALS) 2002-2015. Oral health markers, such as the presence of periodontitis, tooth loss, and dental caries, and the frequency of daily tooth brushing, were evaluated. The primary outcome was the occurrence of retinal vascular occlusions up to December 2015. In total, 2533 participants developed retinal vascular occlusions (215 with retinal artery occlusion, 1686 with retinal vein occlusion, 632 with unspecified retinal vascular occlusion). In the multivariable Cox regression analysis, periodontitis was an independent risk factor for retinal vascular occlusions (adjusted hazard ratio: 1.18; 95% confidence interval: 1.02-1.36; p = 0.024). Frequent tooth brushing was negatively associated with the risk of retinal vascular occlusions (adjusted hazard ratio: 0.89; 95% confidence interval: 0.80-0.98; p = 0.022). Improving oral hygiene may contribute to the attenuation of the risk of retinal vascular occlusions.
- DOI
- 10.3390/jpm13010121
- Appears in Collections:
- 의과대학 > 의학과 > Journal papers
- Files in This Item:
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jpm-13-00121-v2.pdf(635.43 kB)
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