DSpace at EWHA: Clinical predictors of treatment response to tiotropium add-on therapy in adult asthmatic patients: From multicenter real-world cohort data in Korea

Browse

My Repository

View : 271 Download: 88

Full metadata record

DC Field	Value	Language
dc.contributor.author	김민혜	*
dc.contributor.author	심지수	*
dc.date.accessioned	2023-01-06T16:31:07Z	-
dc.date.available	2023-01-06T16:31:07Z	-
dc.date.issued	2022	*
dc.identifier.issn	1939-4551	*
dc.identifier.other	OAK-32742	*
dc.identifier.uri	https://dspace.ewha.ac.kr/handle/2015.oak/263117	-
dc.description.abstract	338489296_20221221170722203 responders; 2) doctor-diagnosed asthma-chronic obstructive pulmonary disease overlap (ACO) [OR = 12.6, 95% CI: 1.8-161.5, P = 0.024], and 3) initial ACT score <20 [OR = 24.1, 95% CI: 5.45- 158.8, P < 0.001] for ACT responders. FEV1 responders also showed a longer exacerbation-free period than those with no FEV1 increase (P = 0.014), yielding a hazard ratio for the first asthma exacerbation of 0.5 (95% CI: 0.3-0.9, P = 0.016). Conclusions: The results of this study suggest that tiotropium add-on for uncontrolled asthma with ICS-LABA would be more effective in patients with positive BDR or ACO. Additionally, an increase in FEV1 following tiotropium may predict a lower risk of asthma exacerbation.	*
dc.language	English	*
dc.publisher	ELSEVIER	*
dc.subject	Tiotropium	*
dc.subject	Muscarinic antagonists	*
dc.subject	Asthma	*
dc.subject	Treatment response	*
dc.subject	Predictor	*
dc.title	Clinical predictors of treatment response to tiotropium add-on therapy in adult asthmatic patients: From multicenter real-world cohort data in Korea	*
dc.type	Article	*
dc.relation.issue	12	*
dc.relation.volume	15	*
dc.relation.index	SCIE	*
dc.relation.index	SCOPUS	*
dc.relation.journaltitle	WORLD ALLERGY ORGANIZATION JOURNAL	*
dc.identifier.doi	10.1016/j.waojou.2022.100720	*
dc.identifier.wosid	WOS:000904490300009	*
dc.identifier.scopusid	2-s2.0-85142432560	*
dc.author.google	Shim, Ji-Su	*
dc.author.google	Jin, Juhae	*
dc.author.google	Kim, Sae-Hoon	*
dc.author.google	Lee, Taehoon	*
dc.author.google	Jang, An-Soo	*
dc.author.google	Park, Chan Sun	*
dc.author.google	Jung, Jae-Woo	*
dc.author.google	Kwon, Jae-Woo	*
dc.author.google	Moon, Ji-Yong	*
dc.author.google	Yang, Min-Suk	*
dc.author.google	Lee, Jaechun	*
dc.author.google	Choi, Jeong-Hee	*
dc.author.google	Shin, Yoo Seob	*
dc.author.google	Kim, Hee-Kyoo	*
dc.author.google	Kim, Sujeong	*
dc.author.google	Kim, Joo-Hee	*
dc.author.google	Cho, Sang-Heon	*
dc.author.google	Nam, Young-Hee	*
dc.author.google	Kim, Sang-Hoon	*
dc.author.google	Park, So Young	*
dc.author.google	Hur, Gyu Young	*
dc.author.google	Kim, Sang-Ha	*
dc.author.google	Park, Hye-Kyung	*
dc.author.google	Jin, Hyun Jung	*
dc.author.google	Lee, Jae-Hyun	*
dc.author.google	Park, Jung-Won	*
dc.author.google	Yoon, Ho Joo	*
dc.author.google	Choi, Byoung Whui	*
dc.author.google	Cho, Young-Joo	*
dc.author.google	Kim, Min-Hye	*
dc.author.google	Kim, Tae-Bum\|Cohort Reality Evolution Adult Ast	*
dc.contributor.scopusid	김민혜(58045929900)	*
dc.contributor.scopusid	심지수(57193221759)	*
dc.date.modifydate	20240315131743	*