Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 김정한 | - |
dc.date.accessioned | 2023-01-06T16:30:09Z | - |
dc.date.available | 2023-01-06T16:30:09Z | - |
dc.date.issued | 2022 | - |
dc.identifier.issn | 1460-2091 | - |
dc.identifier.other | OAK-32794 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/263072 | - |
dc.description.abstract | OBJECTIVES: A substantial number of hospitalized patients with terminal cancer at the end-of-life phase receive antibiotics, even with imminent death. We evaluated the impact of palliative care consultation on antibiotic use in hospitalized patients with terminal cancer during the end-of-life phase. METHODS: We identified adult patients with metastatic solid cancer who died at a tertiary medical centre in Seoul, Republic of Korea, following at least 4 days of hospitalization (January 2018-December 2020). Patients were divided into palliative and non-palliative care consultation groups. Propensity score-weighted, multivariable logistic regression analysis was used to compare the proportion of patients receiving antibiotics within 3 days before death between the two groups. RESULTS: Among 1143 patients analysed, 940 (82.2%) received antibiotics within 3 days before death. The proportion of patients receiving antibiotics was significantly lower (propensity score-weighted P < 0.001) in the palliative care consultation group (344/468; 73.5%) than in the non-palliative care consultation group (596/675; 88.3%). The decrease in the proportion of patients receiving antibiotics in the palliative care consultation group was significant for a carbapenem (42.4% versus 22.4%; P < 0.001), a glycopeptide (23.3% versus 11.1%; P < 0.001) and a quinolone (30.5% versus 19.4%; P = 0.012). In the multivariable logistic regression analysis, receiving palliative care consultation (adjusted OR 0.46, 95% CI 0.33-0.65; P < 0.001) was independently associated with reduced antibiotic use during the end-of-life phase. CONCLUSIONS: Palliative care consultation may reduce aggressive antibiotic use in hospitalized patients with terminal cancer during the end-of-life phase. © The Author(s) 2022. Published by Oxford University Press on behalf of British Society for Antimicrobial Chemotherapy. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com. | - |
dc.language | English | - |
dc.publisher | NLM (Medline) | - |
dc.title | The impact of palliative care consultation on reducing antibiotic overuse in hospitalized patients with terminal cancer at the end of life: a propensity score-weighting study | - |
dc.type | Article | - |
dc.relation.issue | 1 | - |
dc.relation.volume | 78 | - |
dc.relation.index | SCIE | - |
dc.relation.index | SCOPUS | - |
dc.relation.startpage | 302 | - |
dc.relation.lastpage | 308 | - |
dc.relation.journaltitle | The Journal of antimicrobial chemotherapy | - |
dc.identifier.doi | 10.1093/jac/dkac405 | - |
dc.identifier.wosid | WOS:000891972800001 | - |
dc.identifier.scopusid | 2-s2.0-85144595379 | - |
dc.author.google | Kim J.-H. | - |
dc.author.google | Yoo S.H. | - |
dc.author.google | Keam B. | - |
dc.author.google | Heo D.S. | - |
dc.contributor.scopusid | 김정한(55720376100) | - |
dc.date.modifydate | 20230703140406 | - |