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dc.contributor.author편욱범*
dc.date.accessioned2023-01-04T16:30:07Z-
dc.date.available2023-01-04T16:30:07Z-
dc.date.issued2022*
dc.identifier.issn1042-3931*
dc.identifier.issn1557-2501*
dc.identifier.otherOAK-32668*
dc.identifier.urihttps://dspace.ewha.ac.kr/handle/2015.oak/262928-
dc.description.abstractBackground. The optimal duration of dual-antiplatelet therapy (DAPT) after implantation of a drug-eluting stent (DES), especially recently developed polymer-free DESs, is unknown. This study examined the efficacy and safety of 3- versus 6-month DAPT in patients implanted with Coroflex ISAR polymer-free DESs. Methods. Between May 2015 and August 2020, 488 patients who underwent Coroflex ISAR stent implantation were enrolled in the study and randomly assigned to the 3-month (n=244) or 6-month (n=244) DAPT group. Results. At 1 year, the primary endpoint (composite of cardiovascular death, myocardial infarction, target vessel revascularization, and Bleeding Academic Research Consortium [BARC] type 2-5 bleeding) occurred in 9 (3.7%) patients in the 3-month DAPT group and in 7 (2.9%) patients in the 6-month DAPT group (hazard ratio, 1.31; P=.60). There was no difference between the 3- and 6-month DAPT groups in either BARC type 2-5 bleeding (1.6% vs 0.8%; hazard ratio, 2.00; P=.42) or any bleeding (2.9% vs 3.3%; hazard ratio, 0.87; P=.80). Conclusion. Compared with 6 months of DAPT, 3 months of DAPT did not increase the risk of primary endpoint 1 year after Coroflex ISAR stent implantation, although it should be noted that the trial has limited power to see differences due to low event rate and low recruitment rate.*
dc.languageEnglish*
dc.publisherH M P COMMUNICATIONS*
dc.subjectcoronary artery disease*
dc.subjectdrug-eluting stents*
dc.subjectdual-antiplatelet therapy*
dc.subjectduration of therapy*
dc.subjectrandomized controlled trial*
dc.titleEfficacy and Safety of 3 Versus 6 Months of Dual-Antiplatelet Therapy in Patients Implanted With Coroflex ISAR Stents: A Prospective, Multicenter, Randomized Clinical Trial*
dc.typeArticle*
dc.relation.issue9*
dc.relation.volume34*
dc.relation.indexSCIE*
dc.relation.indexSCOPUS*
dc.relation.startpageE653*
dc.relation.lastpage+*
dc.relation.journaltitleJOURNAL OF INVASIVE CARDIOLOGY*
dc.identifier.wosidWOS:000891637300002*
dc.author.googleJin, Uram*
dc.author.googleSeo, Kyoung-Woo*
dc.author.googleYang, Hyoung-Mo*
dc.author.googleLim, Hong-Seok*
dc.author.googleChoi, Byoung-Joo*
dc.author.googleChoi, So-Yeon*
dc.author.googleShin, Joon-Han*
dc.author.googleTahk, Seung-Jea*
dc.author.googleYoo, Sang-Yong*
dc.author.googleRha, Seung Woon*
dc.author.googleChung, Woo-Young*
dc.author.googleKim, Chi-Hoon*
dc.author.googleWon, Ki-Bum*
dc.author.googlePyun, Wook Bum*
dc.author.googleJang, Jae Sik*
dc.author.googleLee, Sung Yun*
dc.author.googleHong, Young Joon*
dc.author.googleKim, Moo Hyun*
dc.author.googleHong, Soon Jun*
dc.author.googleChoi, Yun-Seok*
dc.author.googleKim, Hee-Yeol*
dc.author.googleChoi, Rak Kyeong*
dc.author.googleKang, Woong Chol*
dc.author.googleCho, Eun Joo*
dc.author.googleYoon, Myeong-Ho*
dc.contributor.scopusid편욱범(6508352922)*
dc.date.modifydate20240123092816*
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의과대학 > 의학과 > Journal papers
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