Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 편욱범 | * |
dc.date.accessioned | 2023-01-04T16:30:07Z | - |
dc.date.available | 2023-01-04T16:30:07Z | - |
dc.date.issued | 2022 | * |
dc.identifier.issn | 1042-3931 | * |
dc.identifier.issn | 1557-2501 | * |
dc.identifier.other | OAK-32668 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/262928 | - |
dc.description.abstract | Background. The optimal duration of dual-antiplatelet therapy (DAPT) after implantation of a drug-eluting stent (DES), especially recently developed polymer-free DESs, is unknown. This study examined the efficacy and safety of 3- versus 6-month DAPT in patients implanted with Coroflex ISAR polymer-free DESs. Methods. Between May 2015 and August 2020, 488 patients who underwent Coroflex ISAR stent implantation were enrolled in the study and randomly assigned to the 3-month (n=244) or 6-month (n=244) DAPT group. Results. At 1 year, the primary endpoint (composite of cardiovascular death, myocardial infarction, target vessel revascularization, and Bleeding Academic Research Consortium [BARC] type 2-5 bleeding) occurred in 9 (3.7%) patients in the 3-month DAPT group and in 7 (2.9%) patients in the 6-month DAPT group (hazard ratio, 1.31; P=.60). There was no difference between the 3- and 6-month DAPT groups in either BARC type 2-5 bleeding (1.6% vs 0.8%; hazard ratio, 2.00; P=.42) or any bleeding (2.9% vs 3.3%; hazard ratio, 0.87; P=.80). Conclusion. Compared with 6 months of DAPT, 3 months of DAPT did not increase the risk of primary endpoint 1 year after Coroflex ISAR stent implantation, although it should be noted that the trial has limited power to see differences due to low event rate and low recruitment rate. | * |
dc.language | English | * |
dc.publisher | H M P COMMUNICATIONS | * |
dc.subject | coronary artery disease | * |
dc.subject | drug-eluting stents | * |
dc.subject | dual-antiplatelet therapy | * |
dc.subject | duration of therapy | * |
dc.subject | randomized controlled trial | * |
dc.title | Efficacy and Safety of 3 Versus 6 Months of Dual-Antiplatelet Therapy in Patients Implanted With Coroflex ISAR Stents: A Prospective, Multicenter, Randomized Clinical Trial | * |
dc.type | Article | * |
dc.relation.issue | 9 | * |
dc.relation.volume | 34 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | E653 | * |
dc.relation.lastpage | + | * |
dc.relation.journaltitle | JOURNAL OF INVASIVE CARDIOLOGY | * |
dc.identifier.wosid | WOS:000891637300002 | * |
dc.author.google | Jin, Uram | * |
dc.author.google | Seo, Kyoung-Woo | * |
dc.author.google | Yang, Hyoung-Mo | * |
dc.author.google | Lim, Hong-Seok | * |
dc.author.google | Choi, Byoung-Joo | * |
dc.author.google | Choi, So-Yeon | * |
dc.author.google | Shin, Joon-Han | * |
dc.author.google | Tahk, Seung-Jea | * |
dc.author.google | Yoo, Sang-Yong | * |
dc.author.google | Rha, Seung Woon | * |
dc.author.google | Chung, Woo-Young | * |
dc.author.google | Kim, Chi-Hoon | * |
dc.author.google | Won, Ki-Bum | * |
dc.author.google | Pyun, Wook Bum | * |
dc.author.google | Jang, Jae Sik | * |
dc.author.google | Lee, Sung Yun | * |
dc.author.google | Hong, Young Joon | * |
dc.author.google | Kim, Moo Hyun | * |
dc.author.google | Hong, Soon Jun | * |
dc.author.google | Choi, Yun-Seok | * |
dc.author.google | Kim, Hee-Yeol | * |
dc.author.google | Choi, Rak Kyeong | * |
dc.author.google | Kang, Woong Chol | * |
dc.author.google | Cho, Eun Joo | * |
dc.author.google | Yoon, Myeong-Ho | * |
dc.contributor.scopusid | 편욱범(6508352922) | * |
dc.date.modifydate | 20240123092816 | * |