Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 최희정 | * |
dc.contributor.author | 배지윤 | * |
dc.date.accessioned | 2022-11-03T16:31:07Z | - |
dc.date.available | 2022-11-03T16:31:07Z | - |
dc.date.issued | 2022 | * |
dc.identifier.issn | 2093-2340 | * |
dc.identifier.other | OAK-32460 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/262882 | - |
dc.description.abstract | Background: We investigated cardiovascular disease (CVD), risk factors for CVD, and applicability of the three known CVD risk equations in the Korean human immunodeficiency virus/ Acquired Immune Deficiency Syndrome (HIV/AIDS) cohort. Materials and Methods: The study parcitipants were HIV-infected patients in a Korean HIV/ AIDS cohort enrolled from 19 hospitals between 2006 and 2017. Data collected at entry to the cohort were analyzed. The 5-year CVD risk in each participant was calculated using three CVD risk equations: reduced CVD prediction model of HIV-specific data collection on adverse effects of anti-HIV drugs (R-DAD), Framingham general CVD risk score (FRS), and Korean Coronary Heart Disease Risk Score (KRS). Results: CVD events were observed in 11 of 586 HIV-infected patients during a 5-year (median) follow-up period. The incidence of CVD was 4.11 per 1,000 person-years. Older age (64 vs. 41 years, P = 0.005) and diabetes mellitus (45.5% vs. 6.4%, P <0.001) were more frequent in patients with CVD. Using R-DAD, FRS, and KRS, 1.9%, 2.4%, and 0.7% of patients, respectively, were considered to have a very high risk (≥10%) of 5-year CVD. The discriminatory capacities of the three prediction models were good, with c-statistic values of 0.829 (P <0.001) for R-DAD, 0.824 (P <0.001) for FRS, and 0.850 (P = 0.001) for KRS. Conclusion: The FRS, R-DAD, and KRS performed well in the Korean HIV/AIDS cohort. A larger cohort and a longer period of follow-up may be necessary to demonstrate the risk factors and develop an independent CVD risk prediction model specific to Korean patients with HIV. Provisi © 2022 by The Korean Society. | * |
dc.language | English | * |
dc.publisher | Korean Society of Infectious Diseases, Korean Society for Antimicrobial Therapy, Korean Society for AIDS | * |
dc.subject | Cardiovascular diseases | * |
dc.subject | Coronary disease | * |
dc.subject | HIV | * |
dc.subject | Korea | * |
dc.title | Comparison of Three Cardiovascular Risk Scores among HIV-Infected Patients in Korea: The Korea HIV/AIDS Cohort Study | * |
dc.type | Article | * |
dc.relation.issue | 3 | * |
dc.relation.volume | 54 | * |
dc.relation.index | SCOPUS | * |
dc.relation.journaltitle | Infection and Chemotherapy | * |
dc.identifier.doi | 10.3947/ic.2022.0048 | * |
dc.identifier.scopusid | 2-s2.0-85137414341 | * |
dc.author.google | Bae J.Y. | * |
dc.author.google | Kim S.M. | * |
dc.author.google | Choi Y. | * |
dc.author.google | Choi J.Y. | * |
dc.author.google | Kim S.I. | * |
dc.author.google | Kim S.-W. | * |
dc.author.google | Park B.Y. | * |
dc.author.google | Choi B.Y. | * |
dc.author.google | Choi H.J. | * |
dc.contributor.scopusid | 최희정(57217262202) | * |
dc.contributor.scopusid | 배지윤(57195429959) | * |
dc.date.modifydate | 20240426113129 | * |