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의과대학
의학과
Journal papers
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A Case of Vesicular Mycosis Fungoides
Title
A Case of Vesicular Mycosis Fungoides
Authors
Kim R.
;
Kwon B.R.
;
Byun J.Y.
;
Choi Y.W.
;
Choi H.Y.
;
Park S.
;
Lee M.Y.
Ewha Authors
최혜영
;
최유원
;
박상희
;
변지연
;
이민영
SCOPUS Author ID
최혜영
; 최유원
; 박상희
; 변지연
; 이민영
Issue Date
2022
Journal Title
Annals of Dermatology
ISSN
1013-9087
Citation
Annals of Dermatology vol. 34, no. 5, pp. 374 - 377
Keywords
Mycosis fungoides
;
Vesicular mycosis fungoides
Publisher
Korean Dermatological Association
Indexed
SCIE; SCOPUS; KCI
Document Type
Article
Abstract
A 44-year-old male presented with 7 months history of nonpruritic round oozing plaques on the extremities and red papules on the trunk. The lesions were resistant to topical and oral steroid prescribed at the other local clinics. Histopathological examination showed parakeratosis with acanthosis and rete ridge elongation as well as spongiotic intraepidermal blisters and dense dermal infiltration of small to medium sized atypical lymphoid cells. Immunohistochemical analysis revealed the lymphocyte infiltrate to be predominantly CD4+ T cells, with CD4/CD8 ratio to be greater than 10:1. Infiltration of large cells that were CD30+ were also noted. This histopathologic findings are consistent with vesicular mycosis fungoides (MF). He was prescribed with narrow-band ultraviolet B twice per week and topical steroid, combined with interferon-α injection for 5 weeks, and his skin lesions significantly faded and were flattened. Vesicular MF is associated with poor prognosis, but our patient was able to show benign course of disease thanks to timely diagnosis. One must consider vesicular MF as a differential for recalcitrant eczematous lesions. Copyright © The Korean Dermatological Association and The Korean Society for Investigative Dermatology.
DOI
10.5021/ad.20.100
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