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Miller Fisher syndrome following COVID-19 vaccines: A scoping review
- Title
- Miller Fisher syndrome following COVID-19 vaccines: A scoping review
- Authors
- Kim, Jee-Eun; Yoon, Byeol-A; Kim, Yoo Hwan; Kim, Jong Kuk; Bae, Jong Seok
- Ewha Authors
- 김지은
- SCOPUS Author ID
- 김지은
- Issue Date
- 2022
- Journal Title
- ACTA NEUROLOGICA SCANDINAVICA
- ISSN
- 0001-6314
1600-0404
- Citation
- ACTA NEUROLOGICA SCANDINAVICA vol. 146, no. 5, pp. 604 - 609
- Keywords
- adverse effects; COVID-19 vaccine; Guillain-Barre syndrome; miller Fisher syndrome; systematic review
- Publisher
- WILEY
- Indexed
- SCIE; SCOPUS
- Document Type
- Review
- Abstract
- Background and Purpose Miller Fisher syndrome (MFS), a variant of Guillain-Barre Syndrome (GBS), could be underestimated in evaluations of its adverse events (AEs) following COVID-19 vaccination. We aimed to identify and characterize MFS following COVID-19 vaccination. Materials and Methods Relevant studies reported on during the COVID-19 pandemic were identified in the MEDLINE, Embase, and other databases. Results Nine cases of MFS following COVID-19 vaccination from various regions were included. Unlike MFS following COVID-19 infection, patients with MFS following COVID-19 vaccination frequently presented with anti-GQ1b antibody positivity (44%, 4/9). Unlike GBS following COVID-19 vaccination, only two of nine (22%) cases of MFS following COVID-19 vaccination had developed after viral-vector-related vaccine administration. Conclusions Miller Fisher syndrome following COVID-19 vaccination seems to have a different pathophysiology from MFS following COVID-19 infection and GBS following COVID-19 vaccination. This neurological syndrome with a rare incidence and difficulty in diagnosis should be considered an AE of COVID-19 vaccination.
- DOI
- 10.1111/ane.13687
- Appears in Collections:
- 의료원 > 의료원 > Journal papers
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