Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 박혜숙 | * |
dc.contributor.author | 이혜아 | * |
dc.date.accessioned | 2022-10-27T16:31:31Z | - |
dc.date.available | 2022-10-27T16:31:31Z | - |
dc.date.issued | 2022 | * |
dc.identifier.issn | 2045-2322 | * |
dc.identifier.other | OAK-32256 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/262754 | - |
dc.description.abstract | Using data from the Korean Genome and Epidemiology Study, we identified weight-change patterns during midlife using a group-based trajectory model, and evaluated their associations with the incidence of cardiovascular disease (CVD). At baseline, there were 8774 CVD-free participants. Group-based modeling was used to analyze patterns of weight change over about 16 years. Using multiple model, we evaluated the association between weight-change patterns and CVD risk. During the follow-up period, 741 new CVD cases were identified. The weight-change patterns were characterized as ‘gradual weight gain’, ‘stable weight’, ‘slight weight loss’, and ‘gradual weight loss’. The association between weight-change patterns and CVD risk differed depending on the level of physical activity (PA) at baseline (pinteraction < 0.05). Compared with the stable-weight group, the risk of all CVD (HR 2.5, 95% CI 1.5–4.3) and non-fatal CVD (HR 2.8, 95% CI 1.6–4.9) among the gradual-weight-loss group was apparent in the lowest PA quartile. In addition, on average, a decrease in skeletal-muscle-mass (SMM) levels was observed during the follow-up period, but the decrease in SMM in the gradual-weight-loss group was greater than in the gradual-weight-gain group. Our findings show that gradual weight loss was associated with CVD risk, which was dependent on PA levels. © 2022, The Author(s). | * |
dc.language | English | * |
dc.publisher | Nature Research | * |
dc.title | Association between long-term weight-change trajectory and cardiovascular disease risk by physical activity level | * |
dc.type | Article | * |
dc.relation.issue | 1 | * |
dc.relation.volume | 12 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.journaltitle | Scientific Reports | * |
dc.identifier.doi | 10.1038/s41598-022-17765-0 | * |
dc.identifier.wosid | WOS:000840132800076 | * |
dc.identifier.scopusid | 2-s2.0-85135850931 | * |
dc.author.google | Lee H.A. | * |
dc.author.google | Park H. | * |
dc.contributor.scopusid | 박혜숙(57201862679;56148186100) | * |
dc.contributor.scopusid | 이혜아(57188947704) | * |
dc.date.modifydate | 20240419135248 | * |