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Inodilators May Improve the In-Hospital Mortality of Patients with Cardiogenic Shock Undergoing Veno-Arterial Extracorporeal Membrane Oxygenation
- Title
- Inodilators May Improve the In-Hospital Mortality of Patients with Cardiogenic Shock Undergoing Veno-Arterial Extracorporeal Membrane Oxygenation
- Authors
- Kim, Mijoo; Seong, Seok-Woo; Song, Pil Sang; Jeong, Jin-Ok; Yang, Jeong Hoon; Gwon, Hyeon-Cheol; Ko, Young-Guk; Yu, Cheol Woong; Chun, Woo Jung; Jang, Woo Jin; Kim, Hyun-Joong; Bae, Jang-Whan; Kwon, Sung Uk; Lee, Hyun-Jong; Lee, Wang Soo; Park, Sang-Don; Cho, Sung Soo; Park, Jae-Hyeong
- Ewha Authors
- 장우진
- SCOPUS Author ID
- 장우진
- Issue Date
- 2022
- Journal Title
- JOURNAL OF CLINICAL MEDICINE
- ISSN
- 2077-0383
- Citation
- JOURNAL OF CLINICAL MEDICINE vol. 11, no. 17
- Keywords
- extracorporeal membrane oxygenation; cardiogenic shock; dobutamine; milrinone
- Publisher
- MDPI
- Indexed
- SCIE; SCOPUS
- Document Type
- Article
- Abstract
- Although inodilators (dobutamine and milrinone) are widely used empirically for cardiogenic shock (CS), the efficacy of inodilators for patients with CS undergoing veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is controversial. We evaluated the effects of inodilators on clinical outcomes using the RESCUE (REtrospective and prospective observational Study to investigate Clinical oUtcomes and Efficacy of left ventricular assist device for Korean patients with cardiogenic shock; NCT02985008) registry. We selected and analyzed the clinical outcomes of 496 patients who underwent VA-ECMO and did or did not receive inodilators. Of the 496 patients, 257 (51.8%) died during hospitalization. We selected 191 matched pairs to adjust for baseline clinical characteristics after 1:1 propensity score matching (PSM). The univariate and multivariate analyses showed that the inodilator group had significantly lower in-hospital mortality than the no-inodilator group (unadjusted hazard ratio [HR], 0.768; 95% confidence interval [CI], 0.579-1.018; p = 0.066, adjusted HR, 0.702; 95% CI, 0.552-0.944; p = 0.019). For patients with CS undergoing VA-ECMO, inodilators may improve clinical outcomes.
- DOI
- 10.3390/jcm11174958
- Appears in Collections:
- 의료원 > 의료원 > Journal papers
- Files in This Item:
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