Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 이상은 | - |
dc.date.accessioned | 2022-10-27T16:31:18Z | - |
dc.date.available | 2022-10-27T16:31:18Z | - |
dc.date.issued | 2022 | - |
dc.identifier.issn | 1745-6215 | - |
dc.identifier.other | OAK-32325 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/262691 | - |
dc.description.abstract | Background: Cardiac evaluation using transthoracic echocardiography before noncardiac surgery is common in real-world practice. However, evidence supporting preoperative echocardiography is lacking. This study aims to evaluate the additional benefit of preoperative echocardiography in predicting postoperative cardiovascular events (CVE) in noncardiac surgery. Methods: This study is designed as a multicenter, prospective study to assess the utility of preoperative echocardiography in patients undergoing intermediate- or high-risk noncardiac surgery. This trial comprises two studies: (1) a randomized controlled trial (RCT) for patients undergoing intermediate-risk surgery with fewer than three clinical risk factors from the revised cardiac risk index (intermediate-risk group) and (2) a prospective cohort study for patients undergoing intermediate-risk surgery with three or more clinical risk factors, or who undergo high-risk surgery regardless of the number of clinical risk factors (high-risk group). We hypothesize that the use of preoperative echocardiography will reduce postoperative CVEs in patients undergoing intermediate- to high-risk surgery through discovery of and further intervention for unexpected cardiac abnormalities before elective surgery. A total of 2330 and 2184 patients will be enrolled in the two studies. The primary endpoint is a composite of all-cause death; aborted sudden cardiac arrest; type I acute myocardial infarction; clinically diagnosed unstable angina; stress-induced cardiomyopathy; lethal arrhythmia, such as sustained ventricular tachycardia or ventricular fibrillation; and/or newly diagnosed or acutely decompensated heart failure within 30 days after surgery. Discussion: This study will be the first large-scale prospective study examining the benefit of preoperative echocardiography in predicting postoperative CVE. The PREOP-ECHO trial will help doctors identify patients at risk of postoperative CVE using echocardiography and thereby reduce postoperative CVEs. Trial registration: The Clinical Research Information Service KCT0006279 for RCT and KCT0006280 for prospective cohort study. Registered on June 21, 2021. © 2022, The Author(s). | - |
dc.language | English | - |
dc.publisher | BioMed Central Ltd | - |
dc.subject | Echocardiography | - |
dc.subject | Noncardiac surgery | - |
dc.subject | Trial design | - |
dc.title | PRE-OPerative ECHOcardiograhy for prevention of cardiovascular events after non-cardiac surgery in intermediate- and high-risk patients: protocol for a low-interventional, mixed-cohort prospective study design (PREOP-ECHO) | - |
dc.type | Article | - |
dc.relation.issue | 1 | - |
dc.relation.volume | 23 | - |
dc.relation.index | SCIE | - |
dc.relation.index | SCOPUS | - |
dc.relation.journaltitle | Trials | - |
dc.identifier.doi | 10.1186/s13063-022-06701-2 | - |
dc.identifier.wosid | WOS:000853907300001 | - |
dc.identifier.scopusid | 2-s2.0-85137911799 | - |
dc.author.google | Kim E.K. | - |
dc.author.google | Choi H.-M. | - |
dc.author.google | Choi E.-Y. | - |
dc.author.google | Lee H.S. | - |
dc.author.google | Park G. | - |
dc.author.google | Han D.W. | - |
dc.author.google | Lee S.-E. | - |
dc.author.google | Park C.S. | - |
dc.author.google | Hwang J.-W. | - |
dc.author.google | Choi J.H. | - |
dc.author.google | Kim M.-N. | - |
dc.author.google | Kim H.-K. | - |
dc.author.google | Kim D.-H. | - |
dc.author.google | Shin S.-H. | - |
dc.author.google | Sohn I.S. | - |
dc.author.google | Shin M.-S. | - |
dc.author.google | Na J.O. | - |
dc.author.google | Cho I. | - |
dc.author.google | Lee S.H. | - |
dc.author.google | Park Y.H. | - |
dc.author.google | Park T.-H. | - |
dc.author.google | Kim K.H. | - |
dc.author.google | Cho G.-Y. | - |
dc.author.google | Jung H.O. | - |
dc.author.google | Park D.-G. | - |
dc.author.google | Hong J.Y. | - |
dc.author.google | Kang D.-H. | - |
dc.contributor.scopusid | 이상은(57213176330) | - |
dc.date.modifydate | 20230208112553 | - |