Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이미애 | * |
dc.contributor.author | 정혜선 | * |
dc.contributor.author | 이덕희 | * |
dc.contributor.author | 소민경 | * |
dc.date.accessioned | 2022-10-27T16:31:13Z | - |
dc.date.available | 2022-10-27T16:31:13Z | - |
dc.date.issued | 2022 | * |
dc.identifier.issn | 2075-4418 | * |
dc.identifier.other | OAK-32352 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/262664 | - |
dc.description.abstract | The rapid identification of patients infected with COVID-19 during the SARS-CoV-2 pandemic is critical to operating emergency rooms effectively. Xpert Xpress SARS-CoV-2 (Xpert) assays are increasingly being used in the rapid screening of COVID-19. We evaluated the clinical performance of Xpert by comparing findings with those of qRT-PCR evaluations and included the clinical features of patients visiting the emergency department. Positive results with Xpert testing (n = 370) were compared with qRT-PCR findings, demonstrating a 91.9% intertest agreement. We reviewed the subsequent COVID-19 test results and SARS-CoV-2 infection histories for individuals showing discrepancies in Xpert and qRT-PCR testing and determined whether the findings were truepositive or false-positive. The true-positive rate for Xpert testing was 95.4% (353/370); the remaining 17 samples (4.6%) were false-positive. All false-positive data for Xpert testing showed N2 signals amplified to Ct values of >= 40 with no E gene signals. Rapid Xpert testing is highly sensitive and shows a good performance overall in challenging situations, such as an emergency room. However, we considered the possibility of false-positive Xpert results given an N2 gene signal only, especially given high Ct values. We recommend interpreting test data with caution and considering retesting over time. | * |
dc.language | English | * |
dc.publisher | MDPI | * |
dc.subject | COVID-19 | * |
dc.subject | emergency medicine | * |
dc.subject | rapid screening | * |
dc.subject | qRT-PCR | * |
dc.subject | SARS-CoV-2 | * |
dc.subject | Xpert | * |
dc.title | How Significant Are Xpert Xpress SARS-CoV-2 Test Findings When Only an N2 Gene Is Detected? | * |
dc.type | Article | * |
dc.relation.issue | 9 | * |
dc.relation.volume | 12 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.journaltitle | DIAGNOSTICS | * |
dc.identifier.doi | 10.3390/diagnostics12092133 | * |
dc.identifier.wosid | WOS:000858531500001 | * |
dc.identifier.scopusid | 2-s2.0-85138610546 | * |
dc.author.google | So, Min-Kyung | * |
dc.author.google | Chung, Hae-Sun | * |
dc.author.google | Lee, Duk Hee | * |
dc.author.google | Lee, Miae | * |
dc.contributor.scopusid | 이미애(7409114044) | * |
dc.contributor.scopusid | 정혜선(7404006436) | * |
dc.contributor.scopusid | 이덕희(55698960700) | * |
dc.contributor.scopusid | 소민경(57224742770) | * |
dc.date.modifydate | 20240625081000 | * |