Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 유권 | * |
dc.contributor.author | 허정원 | * |
dc.contributor.author | 김수경 | * |
dc.date.accessioned | 2022-10-27T16:31:05Z | - |
dc.date.available | 2022-10-27T16:31:05Z | - |
dc.date.issued | 2022 | * |
dc.identifier.issn | 1011-8934 | * |
dc.identifier.issn | 1598-6357 | * |
dc.identifier.other | OAK-32390 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/262627 | - |
dc.description.abstract | Although anti-hepatitis A virus (HAV) IgM non-reactive and anti-HAV total (immunoglobulin [Ig] M and IgG) reactive results are generally interpreted as immunity to HAV, some early acute hepatitis A patients show the same results. We compared IgM detection sensitivity between anti-HAV IgM and anti-HAV total assays. Acute hepatitis A patients' samples were serially diluted and tested with Elecsys anti-HAV IgM and total assay (Roche Diagnostics). This resulted in anti-HAV IgM non-reactive but anti-HAV total reactive results. Samples of two hepatitis A patients showing false-negative anti-HAV IgM at initial presentation were analyzed with Elecsys, Atellica (Siemens Healthineers), and Alinity (Abbott Laboratories) HAV assays. Elecsys, Atellica, and Alinity anti-HAV IgM converted reactive on hospital day 3, whereas Elecsys and Atellica anti-HAV total results were reactive from hospital day 1. The anti-HAV total assay had higher sensitivity in detecting IgM antibodies than the anti-HAV IgM assay. | * |
dc.language | English | * |
dc.publisher | KOREAN ACAD MEDICAL SCIENCES | * |
dc.subject | Acute Hepatitis A | * |
dc.subject | Anti-Hepatitis A Virus Immunoglobulin M | * |
dc.subject | Early Acute Phase | * |
dc.title | Assay Sensitivity Difference Can Induce Anti-Hepatitis A Virus IgM Non-Reactive But Total (IgM and IgG) Reactive Results in Early Acute Hepatitis A | * |
dc.type | Article | * |
dc.relation.issue | 37 | * |
dc.relation.volume | 37 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.index | KCI | * |
dc.relation.journaltitle | JOURNAL OF KOREAN MEDICAL SCIENCE | * |
dc.identifier.doi | 10.3346/jkms.2022.37.e287 | * |
dc.identifier.wosid | WOS:000864465400006 | * |
dc.identifier.scopusid | 2-s2.0-85138632394 | * |
dc.author.google | Kim, Soo-Kyung | * |
dc.author.google | Yoo, Kwon | * |
dc.author.google | Huh, Jungwon | * |
dc.contributor.scopusid | 유권(7202592827) | * |
dc.contributor.scopusid | 허정원(7102258576) | * |
dc.contributor.scopusid | 김수경(56013474600;57960989400;58619290500) | * |
dc.date.modifydate | 20240318142540 | * |