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The Korean Organ Transplantation Registry (KOTRY): an overview and summary of the kidney-transplant cohort
- Title
- The Korean Organ Transplantation Registry (KOTRY): an overview and summary of the kidney-transplant cohort
- Authors
- Jeon, Hee Jung; Koo, Tai Yeon; Ju, Man Ki; Chae, Dong-Wan; Choi, Soo Jin Na; Kim, Myoung Soo; Ryu, Jung-Hwa; Jeon, Jong Cheol; Ahn, Curie; Yang, Jaeseok|Korean Organ Transplantat Registry
- Ewha Authors
- 류정화
- SCOPUS Author ID
- 류정화
- Issue Date
- 2022
- Journal Title
- KIDNEY RESEARCH AND CLINICAL PRACTICE
- ISSN
- 2211-9132
2211-9140
- Citation
- KIDNEY RESEARCH AND CLINICAL PRACTICE vol. 41, no. 4, pp. 492 - 507
- Keywords
- Cohort studies; Kidney transplantation; Registries; Republic of Korea
- Publisher
- KOREAN SOC NEPHROLOGY
- Indexed
- SCIE; SCOPUS; KCI
- Document Type
- Article
- Abstract
- Background: As the need for a nationwide organ-transplant registry emerged, a prospective registry, the Korean Organ Transplanta-tion Registry (KOTRY), was initiated in 2014. Here, we present baseline characteristics and outcomes of the kidney-transplant cohort for 2014 through 2019. Methods: The KOTRY consists of five organ-transplant cohorts (kidney, liver, lung, heart, and pancreas). Data and samples were pro-spectively collected from transplant recipients and donors at baseline and follow-up visits; and epidemiological trends, allograft out-comes, and patient outcomes, such as posttransplant complications, comorbidities, and mortality, were analyzed. Results: From 2014 to 2019, there were a total of 6,129 registered kidney transplants (64.8% with living donors and 35.2% with de-ceased donors) with a mean recipient age of 49.4 +/- 11.5 years, and 59.7% were male. ABO-incompatible transplants totaled 17.4% of all transplants, and 15.0% of transplants were preemptive. The overall 1-and 5-year patient survival rates were 98.4% and 95.8%, respectively, and the 1-and 5-year graft survival rates were 97.1% and 90.5%, respectively. During a mean follow-up of 3.8 years, bi-opsy-proven acute rejection episodes occurred in 17.0% of cases. The mean age of donors was 47.3 +/- 12.9 years, and 52.6% were male. Among living donors, the largest category of donors was spouses, while, among deceased donors, 31.2% were expanded -crite-ria donors. The mean serum creatinine concentrations of living donors were 0.78 +/- 0.62 mg/dL and 1.09 +/- 0.24 mg/dL at baseline and 1 year after kidney transplantation, respectively. Conclusion: The KOTRY, a systematic Korean transplant cohort, can serve as a valuable epidemiological database of Korean kidney transplants.
- DOI
- 10.23876/j.krcp.21.185
- Appears in Collections:
- 의과대학 > 의학과 > Journal papers
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