Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 편욱범 | * |
dc.contributor.author | 조인정 | * |
dc.date.accessioned | 2022-07-14T16:30:06Z | - |
dc.date.available | 2022-07-14T16:30:06Z | - |
dc.date.issued | 2022 | * |
dc.identifier.issn | 1738-5520 | * |
dc.identifier.other | OAK-31676 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/261500 | - |
dc.description.abstract | Background and Objectives: This study aimed to investigate the association between cardiovascular events and 2 different levels of elevated on-treatment diastolic blood pressures (DBP) in the presence of achieved systolic blood pressure targets (SBP). Methods: A nation-wide population-based cohort study comprised 237,592 patients with hypertension treated. The primary endpoint was a composite of cardiovascular death, myocardial infarction, and stroke. Elevated DBP was defined according to the Seventh Report of Joint National Committee (JNC7; SBP <140 mmHg, DBP ≥90 mmHg) or to the 2017 American College of Cardiology/American Heart Association (ACC/AHA) definitions (SBP <130 mmHg, DBP ≥80 mmHg). Results: During a median follow-up of 9 years, elevated on-treatment DBP by the JNC7 definition was associated with an increased risk of the occurrence of primary endpoint compared with achieved both SBP and DBP (adjusted hazard ratio [aHR], 1.14; 95% confidence interval [CI], 1.05-1.24) but not in those by the 2017 ACC/AHA definition. Elevated on-treatment DBP by the JNC7 definition was associated with a higher risk of cardiovascular mortality (aHR, 1.42; 95% CI, 1.18-1.70) and stroke (aHR, 1.19; 95% CI, 1.08-1.30). Elevated on-treatment DBP by the 2017 ACC/AHA definition was only associated with stroke (aHR, 1.10; 95% CI, 1.04-1.16). Similar results were seen in the propensity-score-matched cohort. Conclusion: Elevated on-treatment DBP by the JNC7 definition was associated a high risk of major cardiovascular events, while elevated DBP by the 2017 ACC/AHA definition was only associated with a higher risk of stroke. The result of study can provide evidence of DBP targets in subjects who achieved SBP targets. © 2022 Korean Society of Circulation. All rights reserved. | * |
dc.language | English | * |
dc.publisher | Korean Society of Circulation | * |
dc.subject | Blood pressure | * |
dc.subject | Hypertension | * |
dc.title | Elevated On-Treatment Diastolic Blood Pressure and Cardiovascular Outcomes in the Presence of Achieved Systolic Blood Pressure Targets | * |
dc.type | Article | * |
dc.relation.volume | 52 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.index | KCI | * |
dc.relation.journaltitle | Korean Circulation Journal | * |
dc.identifier.doi | 10.4070/kcj.2021.0330 | * |
dc.identifier.wosid | WOS:000810362600007 | * |
dc.identifier.scopusid | 2-s2.0-85127025962 | * |
dc.author.google | Kim D.-H. | * |
dc.author.google | Cho I.-J. | * |
dc.author.google | Kim W. | * |
dc.author.google | Lee C.J. | * |
dc.author.google | Kim H.-C. | * |
dc.author.google | Shin J.-H. | * |
dc.author.google | Kang S.-H. | * |
dc.author.google | Jung M.-H. | * |
dc.author.google | Kwon C.H. | * |
dc.author.google | Lee J.-H. | * |
dc.author.google | Kim H.L. | * |
dc.author.google | Kim H.M. | * |
dc.author.google | Cho I. | * |
dc.author.google | Kang D.R. | * |
dc.author.google | Lee H.-Y. | * |
dc.author.google | Chung W.-J. | * |
dc.author.google | Kim K.I. | * |
dc.author.google | Cho E.J. | * |
dc.author.google | Sohn I.-S. | * |
dc.author.google | Park S. | * |
dc.author.google | Shin J. | * |
dc.author.google | Ryu S.K. | * |
dc.author.google | Kang S.-M. | * |
dc.author.google | Pyun W.B. | * |
dc.author.google | Cho M.-C. | * |
dc.author.google | Kim J.H. | * |
dc.author.google | Lee J.H. | * |
dc.author.google | Ihm S.-H. | * |
dc.author.google | Sung K.-C. | * |
dc.contributor.scopusid | 편욱범(6508352922) | * |
dc.contributor.scopusid | 조인정(26537053500) | * |
dc.date.modifydate | 20240123092816 | * |