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의과대학
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Journal papers
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Breast Cancer after Radiation Therapy in a Patient with Li-Fraumeni Syndrome: A Case Report
Title
Breast Cancer after Radiation Therapy in a Patient with Li-Fraumeni Syndrome: A Case Report
Authors
Yoon I.N.
;
Cha E.S.
;
Kim J.H.
;
Lee J.E.
;
Chung J.
Ewha Authors
차은숙
;
이지은
;
정진
;
김정현
SCOPUS Author ID
차은숙
; 이지은
; 정진
; 김정현
Issue Date
2022
Journal Title
Journal of the Korean Society of Radiology
ISSN
1738-2637
Citation
Journal of the Korean Society of Radiology vol. 83, no. 1, pp. 246 - 251
Keywords
Breast Neoplasms
;
Li-Fraumeni Syndrome
;
Sarcoma
;
Second Primary
Publisher
Korean Radiological Society
Indexed
SCOPUS; KCI
Document Type
Article
Abstract
Li-Fraumeni syndrome (LFS) is an inherited autosomal-dominant tumor-predisposition disorder caused by germline mutations in the TP53 tumor suppressor gene. Since patients with LFS are likely to develop therapy-related cancers, radiation therapy should be avoided if breast cancer is found in these individuals. Herein, we present a case of secondary breast cancer in an LFS patient after radiation and chemotherapy for the first diagnosed breast sarcoma. © 2022 Korean Radiological Society. All right reserved.
DOI
10.3348/jksr.2021.0045
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