Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 김충기 | * |
dc.date.accessioned | 2022-02-28T16:30:03Z | - |
dc.date.available | 2022-02-28T16:30:03Z | - |
dc.date.issued | 2022 | * |
dc.identifier.issn | 1936-878X | * |
dc.identifier.other | OAK-30659 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/260735 | - |
dc.description.abstract | Objectives: This study sought to evaluate the impact of poststent optical coherence tomography (OCT) findings, including severe malapposition, on long-term clinical outcomes. Background: Suboptimal OCT findings following percutaneous coronary intervention (PCI) are highly prevalent; however, their clinical implications remain controversial. Methods: Of the patients registered in the Yonsei OCT registry, a total of 1,290 patients with 1,348 lesions, who underwent OCT immediately poststenting, were consecutively enrolled for this study. All patients underwent implantation of drug-eluting stents. Poststent OCT findings were assessed to identify predictors of device-oriented clinical endpoints (DoCE), including cardiac death, target vessel-related myocardial infarction (MI) or stent thrombosis, and target lesion revascularization (TLR). Significant malapposition criteria associated with major safety events (MSE) were also investigated, such as cardiac death, target vessel-related MI, or stent thrombosis. Results: The median follow-up period was 43.0 months (interquartile range [IQR] 21.4 to 56.0 months). The incidence rates of stent edge dissection, tissue prolapse, thrombus, and malapposition after intervention were not associated with occurrence of DoCE. However, patients with significant malapposition (total malapposition volume [TMV] ≥7.0 mm3] exhibited more frequent MSE. A smaller minimal stent area (MSA) was identified as an independent predictor for DoCE (hazard ratio [HR]: 1.20 [95% confidence interval [CI]: 1.00 to 1.43]; p = 0.045). Malapposition with TMV ≥7.0 mm3 was found to be an independent predictor of MSE (HR: 6.12 [95% CI: 1.88 to 19.95]; p = 0.003). Follow-up OCT at 3, 6, or 9 months after PCI showed that poststent TMV ≥7.0 mm3 was related to a greater occurrence of late malapposition and uncovered struts. Conclusions: Although most suboptimal OCT findings were not associated with clinical outcomes, a smaller MSA was associated with DoCE, driven mainly by TLR, and significant malapposition with TMV ≥7.0 mm3 was associated with more MSE after PCI. (Yonsei OCT [Optical Coherence Tomography] Registry for Evaluation of Efficacy and Safety of Coronary Stenting; Yonsei OCT registry; NCT02099162) © 2022 American College of Cardiology Foundation | * |
dc.language | English | * |
dc.publisher | Elsevier Inc. | * |
dc.subject | drug-eluting stent(s) | * |
dc.subject | malapposition | * |
dc.subject | optical coherence tomography | * |
dc.subject | percutaneous coronary intervention | * |
dc.subject | total malapposition volume | * |
dc.title | Clinical Implications of Poststent Optical Coherence Tomographic Findings: Severe Malapposition and Cardiac Events | * |
dc.type | Article | * |
dc.relation.issue | 1 | * |
dc.relation.volume | 15 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 126 | * |
dc.relation.lastpage | 137 | * |
dc.relation.journaltitle | JACC: Cardiovascular Imaging | * |
dc.identifier.doi | 10.1016/j.jcmg.2021.03.008 | * |
dc.identifier.wosid | WOS:000741760700017 | * |
dc.identifier.scopusid | 2-s2.0-85107314740 | * |
dc.author.google | Kim B.G. | * |
dc.author.google | Kachel M. | * |
dc.author.google | Kim J.-S. | * |
dc.author.google | Guagliumi G. | * |
dc.author.google | Kim C. | * |
dc.author.google | Kim I.-S. | * |
dc.author.google | Lee Y.-J. | * |
dc.author.google | Lee O.-H. | * |
dc.author.google | Byun Y.S. | * |
dc.author.google | Kim B.O. | * |
dc.author.google | Milewski K. | * |
dc.author.google | Lee S.-J. | * |
dc.author.google | Hong S.-J. | * |
dc.author.google | Ahn C.-M. | * |
dc.author.google | Shin D.-H. | * |
dc.author.google | Kim B.-K. | * |
dc.author.google | Ko Y.-G. | * |
dc.author.google | Choi D. | * |
dc.author.google | Jang Y. | * |
dc.contributor.scopusid | 김충기(55697727500) | * |
dc.date.modifydate | 20240422141740 | * |