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Association between CHADS2, CHA2 DS2-VASc, ATRIA, and Essen Stroke Risk Scores and Unsuccessful Recanalization after Endovascular Thrombectomy in Acute Ischemic Stroke Patients
- Title
- Association between CHADS2, CHA2 DS2-VASc, ATRIA, and Essen Stroke Risk Scores and Unsuccessful Recanalization after Endovascular Thrombectomy in Acute Ischemic Stroke Patients
- Authors
- Kim H.J.; Park M.-S.; Yoo J.; Kim Y.D.; Park H.; Kim B.M.; Bang O.Y.; Kim H.C.; Han E.; Kim D.J.; Heo J.; Choi J.K.; Lee K.-Y.; Lee H.S.; Shin D.H.; Choi H.-Y.; Sohn S.-I.; Hong J.-H.; Lee J.Y.; Baek J.-H.; Kim G.S.; Seo W.-K.; Chung J.-W.; Kim S.H.; Han S.W.; Park J.H.; Kim J.; Jung Y.H.; Cho H.-J.; Ahn S.H.; Lee S.I.; Seo K.-D.; Chang Y.; Song T.-J.; Nam H.S.
- Ewha Authors
- 송태진; 김형준; 박무석
- SCOPUS Author ID
- 송태진; 김형준; 박무석
- Issue Date
- 2022
- Journal Title
- Journal of Clinical Medicine
- ISSN
- 2077-0383
- Citation
- Journal of Clinical Medicine vol. 11, no. 1
- Keywords
- Ischemic stroke; Recanalization; Stroke risk score; Thrombectomy
- Publisher
- MDPI
- Indexed
- SCIE; SCOPUS
- Document Type
- Article
- Abstract
- Background: The CHADS2, CHA2 DS2-VASc, ATRIA, and Essen scores have been developed for predicting vascular outcomes in stroke patients. We investigated the association between these stroke risk scores and unsuccessful recanalization after endovascular thrombectomy (EVT). Methods: From the nationwide multicenter registry (Selection Criteria in Endovascular Thrombectomy and Thrombolytic therapy (SECRET)) (Clinicaltrials.gov NCT02964052), we consecutively included 501 patients who underwent EVT. We identified pre-admission stroke risk scores in each included patient. Results: Among 501 patients who underwent EVT, 410 (81.8%) patients achieved successful recanalization (mTICI ≥ 2b). Adjusting for body mass index and p < 0.1 in univariable analysis revealed the association between all stroke risk scores and unsuccessful recanalization (CHADS2 score: odds ratio (OR) 1.551, 95% confidence interval (CI) 1.198–2.009, p = 0.001; CHA2 DS2 VASc score: OR 1.269, 95% CI 1.080–1.492, p = 0.004; ATRIA score: OR 1.089, 95% CI 1.011–1.174, p = 0.024; and Essen score: OR 1.469, 95% CI 1.167–1.849, p = 0.001). The CHADS2 score had the highest AUC value and differed significantly only from the Essen score (AUC of CHADS2 score; 0.618, 95% CI 0.554–0.681). Conclusion: All stroke risk scores were associated with unsuccessful recanalization after EVT. Our study suggests that these stroke risk scores could be used to predict recanalization in stroke patients undergoing EVT. © 2022 by the authors. Licensee MDPI, Basel, Switzerland.
- DOI
- 10.3390/jcm11010274
- Appears in Collections:
- 의과대학 > 의학과 > Journal papers
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