Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 태정현 | * |
dc.date.accessioned | 2021-11-10T16:31:28Z | - |
dc.date.available | 2021-11-10T16:31:28Z | - |
dc.date.issued | 2021 | * |
dc.identifier.issn | 1976-2283 | * |
dc.identifier.issn | 2005-1212 | * |
dc.identifier.other | OAK-30383 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/259437 | - |
dc.description.abstract | Background/Aims: This study examined the long-term outcomes of undifferentiated-type early gastric cancer (UD EGC) with positive horizontal margins (HMs) after endoscopic resection (ER) and compared them between additional surgery and nonsurgical management. Methods: From 2005 to 2015, a total of 1,124 patients with UD EGC underwent ER at 18 tertiary hospitals in Korea. Of them, 92 patients with positive HMs as the only noncurative factor (n=25) or with both positive HMs and tumor size >2 cm (n=67) were included. These patients underwent additional surgery (n=40), underwent additional endoscopic treatment (n=6), or were followed up without further treatment (n=46). Results: No lymph node (LN) metastasis was found in patients who underwent additional surgery. During a median follow-up of 57.7 months (interquartile range, 27.6 to 68.8 months), no LN or distant metastases or gastric cancer-related deaths occurred in the overall cohort. At baseline, the residual cancer rate was 57.8% (26/45) after additional surgery or ER. The 5-year local recurrence rate was 33.6% among patients who were followed up without additional treatment. The 5-year overall survival rates were 95.0% and 87.8% after additional surgery and nonsurgical management (endoscopic treatment or close follow-up), respectively (log-rank p=0.224). In the multivariate Cox regression analysis, nonsurgical management was not associated with an increased risk of mortality. Conclusions: UD EGC with positive HMs after ER may have favorable long-term outcomes and a very low risk of LN metastasis. Nonsurgical management may be suggested as an alternative, particularly for patients with old age or chronic illness. (Gut Liver 2021;15:723-731) | * |
dc.language | English | * |
dc.publisher | EDITORIAL OFFICE GUT & | * |
dc.publisher | LIVER | * |
dc.subject | Stomach neoplasms | * |
dc.subject | Undifferentiated-type histology | * |
dc.subject | Endoscopic mucosal resec-tion | * |
dc.subject | Margins of excision | * |
dc.subject | Lymphatic metastasis | * |
dc.title | Long-term Outcomes of Undifferentiated-Type Early Gastric Cancer with Positive Horizontal Margins after Endoscopic Resection | * |
dc.type | Article | * |
dc.relation.issue | 5 | * |
dc.relation.volume | 15 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.index | KCI | * |
dc.relation.startpage | 723 | * |
dc.relation.lastpage | 731 | * |
dc.relation.journaltitle | GUT AND LIVER | * |
dc.identifier.doi | 10.5009/gnl20291 | * |
dc.identifier.wosid | WOS:000736815600002 | * |
dc.identifier.scopusid | 2-s2.0-85115217950 | * |
dc.author.google | Yang, Hyo-Joon | * |
dc.author.google | Lee, Wan-Sik | * |
dc.author.google | Lee, Bong Eun | * |
dc.author.google | Ahn, Ji Yong | * |
dc.author.google | Jang, Jae-Young | * |
dc.author.google | Lim, Joo Hyun | * |
dc.author.google | Nam, Su Youn | * |
dc.author.google | Kim, Jie-Hyun | * |
dc.author.google | Min, Byung-Hoon | * |
dc.author.google | Joo, Moon Kyung | * |
dc.author.google | Park, Jae Myung | * |
dc.author.google | Shin, Woon Geon | * |
dc.author.google | Lee, Hang Lak | * |
dc.author.google | Gweon, Tae-Geun | * |
dc.author.google | Park, Moo In | * |
dc.author.google | Choi, Jeongmin | * |
dc.author.google | Tae, Chung Hyun | * |
dc.author.google | Kim, Young-Il | * |
dc.author.google | Choi, Il Ju | * |
dc.contributor.scopusid | 태정현(35211966400) | * |
dc.date.modifydate | 20240308140308 | * |