View : 396 Download: 0

Full metadata record

DC Field Value Language
dc.contributor.author태정현*
dc.date.accessioned2021-11-10T16:31:28Z-
dc.date.available2021-11-10T16:31:28Z-
dc.date.issued2021*
dc.identifier.issn1976-2283*
dc.identifier.issn2005-1212*
dc.identifier.otherOAK-30383*
dc.identifier.urihttps://dspace.ewha.ac.kr/handle/2015.oak/259437-
dc.description.abstractBackground/Aims: This study examined the long-term outcomes of undifferentiated-type early gastric cancer (UD EGC) with positive horizontal margins (HMs) after endoscopic resection (ER) and compared them between additional surgery and nonsurgical management. Methods: From 2005 to 2015, a total of 1,124 patients with UD EGC underwent ER at 18 tertiary hospitals in Korea. Of them, 92 patients with positive HMs as the only noncurative factor (n=25) or with both positive HMs and tumor size >2 cm (n=67) were included. These patients underwent additional surgery (n=40), underwent additional endoscopic treatment (n=6), or were followed up without further treatment (n=46). Results: No lymph node (LN) metastasis was found in patients who underwent additional surgery. During a median follow-up of 57.7 months (interquartile range, 27.6 to 68.8 months), no LN or distant metastases or gastric cancer-related deaths occurred in the overall cohort. At baseline, the residual cancer rate was 57.8% (26/45) after additional surgery or ER. The 5-year local recurrence rate was 33.6% among patients who were followed up without additional treatment. The 5-year overall survival rates were 95.0% and 87.8% after additional surgery and nonsurgical management (endoscopic treatment or close follow-up), respectively (log-rank p=0.224). In the multivariate Cox regression analysis, nonsurgical management was not associated with an increased risk of mortality. Conclusions: UD EGC with positive HMs after ER may have favorable long-term outcomes and a very low risk of LN metastasis. Nonsurgical management may be suggested as an alternative, particularly for patients with old age or chronic illness. (Gut Liver 2021;15:723-731)*
dc.languageEnglish*
dc.publisherEDITORIAL OFFICE GUT &amp*
dc.publisherLIVER*
dc.subjectStomach neoplasms*
dc.subjectUndifferentiated-type histology*
dc.subjectEndoscopic mucosal resec-tion*
dc.subjectMargins of excision*
dc.subjectLymphatic metastasis*
dc.titleLong-term Outcomes of Undifferentiated-Type Early Gastric Cancer with Positive Horizontal Margins after Endoscopic Resection*
dc.typeArticle*
dc.relation.issue5*
dc.relation.volume15*
dc.relation.indexSCIE*
dc.relation.indexSCOPUS*
dc.relation.indexKCI*
dc.relation.startpage723*
dc.relation.lastpage731*
dc.relation.journaltitleGUT AND LIVER*
dc.identifier.doi10.5009/gnl20291*
dc.identifier.wosidWOS:000736815600002*
dc.identifier.scopusid2-s2.0-85115217950*
dc.author.googleYang, Hyo-Joon*
dc.author.googleLee, Wan-Sik*
dc.author.googleLee, Bong Eun*
dc.author.googleAhn, Ji Yong*
dc.author.googleJang, Jae-Young*
dc.author.googleLim, Joo Hyun*
dc.author.googleNam, Su Youn*
dc.author.googleKim, Jie-Hyun*
dc.author.googleMin, Byung-Hoon*
dc.author.googleJoo, Moon Kyung*
dc.author.googlePark, Jae Myung*
dc.author.googleShin, Woon Geon*
dc.author.googleLee, Hang Lak*
dc.author.googleGweon, Tae-Geun*
dc.author.googlePark, Moo In*
dc.author.googleChoi, Jeongmin*
dc.author.googleTae, Chung Hyun*
dc.author.googleKim, Young-Il*
dc.author.googleChoi, Il Ju*
dc.contributor.scopusid태정현(35211966400)*
dc.date.modifydate20240308140308*
Appears in Collections:
의과대학 > 의학과 > Journal papers
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

BROWSE