Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 장우진 | * |
dc.date.accessioned | 2021-08-12T16:32:38Z | - |
dc.date.available | 2021-08-12T16:32:38Z | - |
dc.date.issued | 2021 | * |
dc.identifier.issn | 2055-5822 | * |
dc.identifier.other | OAK-29806 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/258852 | - |
dc.description.abstract | Aims: This study aimed to investigate differences in baseline and treatment characteristics, and in-hospital mortality according to the aetiologies of cardiogenic shock in patients undergoing veno-arterial-extracorporeal membrane oxygenation (VA-ECMO). Methods and results: The RESCUE registry is a multicentre, observational cohort that includes 1247 patients with cardiogenic shock from 12 centres. A total of 496 patients requiring VA-ECMO were finally selected, and the study population was stratified by cardiogenic shock aetiology [ischaemic cardiomyopathy (ICM, n = 342) and non-ICM (NICM, n = 154)]. The primary outcome of interest was in-hospital mortality. Sensitivity analyses including propensity-score matching adjustments were performed. Mean age of the entire population was 61.8 ± 14.2, and 30.8% were women. There were significant differences in baseline characteristics; notable differences included the older age of patients with ICM (65.1 ± 13.7 vs. 58.2 ± 13.8, P < 0.001), preponderance of males [258 (75.4%) vs. 85 (55.2%), P < 0.001], and higher prevalence of diabetes mellitus [140 (40.9%) vs. 39 (25.3%), P = 0.001] compared with patients in the NICM aetiology group. Patients with ischaemic cardiogenic shock were more likely to have longer shock duration before VA-ECMO implantation (518.7 ± 941.4 min vs. 292.4 ± 707.8 min, P = 0.003) and were less likely to undergo distal limb perfusion than those with NICM [108 (31.6%) vs. 79 (51.3%), P < 0.001]. In-hospital mortality in the overall cohort was 52.2%; patients with ICM had a higher unadjusted risk of in-hospital mortality [203 (59.4%) vs. 56 (36.4%); unadjusted hazard ratio, 2.295; 95% confidence interval, 1.698–3.100; P < 0.001]. There were no significant differences in the primary outcome between the two aetiologies following propensity-score matching multiple adjustments (adjusted hazard ratio, 1.265; 95% confidence interval, 0.840–1.906; P = 0.260). Conclusions: Results of the current study indicated among patients with cardiogenic shock undergoing VA-ECMO, ischaemic aetiology does not seem to impact in-hospital mortality. These findings underline that early initiation and appropriate treatment strategies of VA-ECMO for patients with ICM shock are required. © 2021 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology. | * |
dc.language | English | * |
dc.publisher | John Wiley and Sons Inc | * |
dc.subject | Cardiogenic shock | * |
dc.subject | ECMO | * |
dc.subject | Ischaemic cardiomyopathy | * |
dc.subject | Non-ischaemic cardiomyopathy | * |
dc.title | Comparison of in-hospital outcomes of patients with vs. without ischaemic cardiomyopathy undergoing veno-arterial-extracorporeal membrane oxygenation | * |
dc.type | Article | * |
dc.relation.issue | 4 | * |
dc.relation.volume | 8 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 3308 | * |
dc.relation.lastpage | 3315 | * |
dc.relation.journaltitle | ESC Heart Failure | * |
dc.identifier.doi | 10.1002/ehf2.13481 | * |
dc.identifier.scopusid | 2-s2.0-85107927737 | * |
dc.author.google | Seong S.-W. | * |
dc.author.google | Jin G. | * |
dc.author.google | Kim M. | * |
dc.author.google | Ahn K.T. | * |
dc.author.google | Yang J.H. | * |
dc.author.google | Gwon H.-C. | * |
dc.author.google | Ko Y.-G. | * |
dc.author.google | Yu C.W. | * |
dc.author.google | Chun W.J. | * |
dc.author.google | Jang W.J. | * |
dc.author.google | Kim H.-J. | * |
dc.author.google | Bae J.-W. | * |
dc.author.google | Kwon S.U. | * |
dc.author.google | Lee H.-J. | * |
dc.author.google | Lee W.S. | * |
dc.author.google | Park S.-D. | * |
dc.author.google | Cho S.S. | * |
dc.author.google | Ahn J.H. | * |
dc.author.google | Song P.S. | * |
dc.author.google | Jeong J.-O. | * |
dc.contributor.scopusid | 장우진(57212421225;56522417800) | * |
dc.date.modifydate | 20240426132658 | * |