Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 한수정 | * |
dc.date.accessioned | 2021-06-07T16:31:26Z | - |
dc.date.available | 2021-06-07T16:31:26Z | - |
dc.date.issued | 2021 | * |
dc.identifier.issn | 1471-2202 | * |
dc.identifier.other | OAK-29367 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/257623 | - |
dc.description.abstract | Background: Balance impairment and lack of postural orientation are serious problems in patients with repetitive mild traumatic brain injury (mTBI). Objective: To investigate whether anodal transcranial direct current stimulation (tDCS) over the primary motor cortex (M1) can improve balance control and gait in repetitive mTBI rat models. Methods: In this prospective animal study, 65 repetitive mTBI rats were randomly assigned to two groups: the tDCS group and the control group. To create repetitive mTBI model rats, we induced mTBI in the rats for 3 consecutive days. The tDCS group received one session of anodal tDCS over the M1 area 24 h after the third induced mTBI, while the control group did not receive tDCS treatment. Motor-evoked potential (MEP), foot-fault test, and rotarod test were evaluated before mTBI, before tDCS and after tDCS. The Mann–Whitney U test and Wilcoxon signed rank test were used to assess the effects of variables between the two groups. Results: Anodal tDCS over the M1 area significantly improved the amplitude of MEP in the tDCS group (p = 0.041). In addition, rotarod duration was significantly increased in the tDCS group (p = 0.001). The foot-fault ratio was slightly lower in the tDCS group, however, this was not statistically significant. Conclusion: Anodal tDCS at the M1 area could significantly improve the amplitude of MEP and balance function in a repetitive mTBI rat model. We expect that anodal tDCS would have the potential to improve balance in patients with repetitive mTBI. © 2021, The Author(s). | * |
dc.language | English | * |
dc.publisher | BioMed Central Ltd | * |
dc.subject | Balance | * |
dc.subject | Mild traumatic brain injury | * |
dc.subject | Motor evoked potential | * |
dc.subject | TDCS | * |
dc.title | Transcranial direct current stimulation for balance and gait in repetitive mild traumatic brain injury in rats | * |
dc.type | Article | * |
dc.relation.issue | 1 | * |
dc.relation.volume | 22 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.journaltitle | BMC Neuroscience | * |
dc.identifier.doi | 10.1186/s12868-021-00633-4 | * |
dc.identifier.wosid | WOS:000640845500001 | * |
dc.identifier.scopusid | 2-s2.0-85104401509 | * |
dc.author.google | Park G. | * |
dc.author.google | Suh J.H. | * |
dc.author.google | Han S.J. | * |
dc.contributor.scopusid | 한수정(57217617482) | * |
dc.date.modifydate | 20240123093411 | * |