View : 540 Download: 0
Adherence to follow-up examination after positive fecal occult blood test results affects colorectal cancer mortality: A Korea population-based cohort study
- Title
- Adherence to follow-up examination after positive fecal occult blood test results affects colorectal cancer mortality: A Korea population-based cohort study
- Authors
- Kim Y.J.; Shim J.-I.; Park E.; Kang M.; Kang S.; Lee J.; Tchoe H.J.; Kong K.A.; Kim D.H.; Kim B.C.; Choi K.S.; Moon C.M.
- Ewha Authors
- 문창모; 공경애
- SCOPUS Author ID
- 문창모; 공경애
- Issue Date
- 2021
- Journal Title
- Digestive and Liver Disease
- ISSN
- 1590-8658
- Citation
- Digestive and Liver Disease vol. 53, no. 5, pp. 631 - 638
- Keywords
- Adherence; Colonoscopy; Colorectal cancer; Fecal occult blood test; Follow-up
- Publisher
- Elsevier B.V.
- Indexed
- SCIE; SCOPUS
- Document Type
- Article
- Abstract
- Background: The impact of adherence to follow-up examination after a fecal occult blood test (FOBT) remains ill-defined. Aim: To evaluate the impact of adherence to the follow-up examination on clinical outcomes in individuals with positive FOBT results. Methods: This was a retrospective cohort study involving Korean individuals aged 50 years or older who participated in the National Cancer Screening Program for CRC from 2009 to 2010. Individuals who underwent a confirmative examination within a year after positive FOBT results were included in compliant group, and those who did not were included in non-compliant group. The incidence and stage of CRC, and 5-year survival were compared between two groups. Results: 5,914 were diagnosed with CRC in the compliant group and 2,973 in the non-compliant group. The proportion of advanced-stage CRC was significantly higher in the non-compliant group (localized CRC 44.6% vs. 36.7% and distant CRC 8.7% vs. 12.5%, p< 0.0001). The survival probability within 5 years was 71.0% in the non-compliant group and 85.9% in the compliant group (hazard ratio 1.70, 95% CI, 1.52–1.90, p< 0.001). Conclusion: Individuals who underwent follow-up examination 1 year or more after positive FOBT had a lower survival rate compared with that in those who underwent examination within 1 year. © 2021 Editrice Gastroenterologica Italiana S.r.l.
- DOI
- 10.1016/j.dld.2021.02.007
- Appears in Collections:
- 의과대학 > 의학과 > Journal papers
- Files in This Item:
There are no files associated with this item.
- Export
- RIS (EndNote)
- XLS (Excel)
- XML