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Sleep disorders in patients with functional dyspepsia: A multicenter study from the Korean Society of Neurogastroenterology and Motility
- Title
- Sleep disorders in patients with functional dyspepsia: A multicenter study from the Korean Society of Neurogastroenterology and Motility
- Authors
- Park, Jong Kyu; Huh, Kyu Chan; Kwon, Joong Goo; Jung, Kee Wook; Oh, Jung Hwan; Song, Kyung Ho; Jung, Kyoungwon; Bang, Ki Bae; Lee, Ju Yup; Tae, Chung Hyun; Shin, Cheol Min; Kim, Jong Wook; Lee, Hyuk
- Ewha Authors
- 태정현
- SCOPUS Author ID
- 태정현
- Issue Date
- 2021
- Journal Title
- JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
- ISSN
- 0815-9319
1440-1746
- Citation
- JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY vol. 36, no. 3, pp. 687 - 693
- Keywords
- Anxiety; Dyspepsia; Heartburn; Sleep disorder
- Publisher
- WILEY
- Indexed
- SCIE; SCOPUS
- Document Type
- Article
- Abstract
- Background and Aim The few studies concerning the association between sleep disorders and functional dyspepsia (FD) have yielded inconsistent results. We compared the prevalence of sleep disorders in patients with FD and healthy controls, and evaluated whether FD was independently associated with sleep disorders, and the risk factors for sleep disorders in patients with FD. Methods This prospective, multicenter, cross-sectional study was conducted from August 2014 to December 2017 at 12 hospitals in South Korea. The inclusion criterion was the presence of FD (for >= 18 years) according to the Rome III criteria. Healthy controls were recruited from among patients who visited the Health Examination Center for check-ups. Results In total, 526 subjects were prospectively enrolled in this study (201 with FD and 325 healthy controls). The prevalence of sleep disorders was significantly higher among the patients with FD than among the healthy controls (41.8%vs18.8%,P = 0.000). In a multivariate analysis, FD (odds ratio [OR] = 1.851; 95% confidence interval [CI] 1.194-2.870;P = 0.006), female sex (OR = 1.672; 95% CI 1.063-2.628;P = 0.026), and anxiety (OR = 3.325; 95% CI 2.140-5.166;P = 0.000) were independent risk factors for sleep disorders in the overall cohorts. In patients with FD only, low body mass index, heartburn, and anxiety were independent risk factors for sleep disorders in a further multivariate analysis. Conclusion Sleep disorders were common in patients with FD. FD was significantly associated with sleep disorders in our patient population, irrespective of the presence of heartburn or psychiatric disorders.
- DOI
- 10.1111/jgh.15198
- Appears in Collections:
- 의과대학 > 의학과 > Journal papers
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