Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 박준범 | * |
dc.date.accessioned | 2021-05-28T16:30:46Z | - |
dc.date.available | 2021-05-28T16:30:46Z | - |
dc.date.issued | 2021 | * |
dc.identifier.issn | 2055-5822 | * |
dc.identifier.other | OAK-29125 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/257428 | - |
dc.description.abstract | Aims: This study aimed to elucidate the risk for stroke and systemic embolism (SE) in patients with atrial fibrillation and heart failure (HF) according to HF type. Methods and results: A total of 10 780 patients with atrial fibrillation were enrolled in a multicentre prospective registry and divided according to HF type: no-HF, HF with preserved ejection fraction (EF) (HFpEF), HF with mid-range EF (HFmrEF), and HF with reduced EF (HFrEF). Each group included 237 age-matched and sex-matched patients (age, 69.0 ± 10.3 years; men, 69.6%). The baseline characteristics, cumulative incidence, and hazard ratios for stroke/SE and major bleeding were compared across the groups. Patients with HF accounted for 10.3% of the total population; HFpEF, HFmrEF, and HFrEF represented 43.7%, 23.6%, and 32.7% of the patients with HF, respectively. The CHA2DS2-VASc score was significantly higher in the HFpEF, HFmrEF, and HFrEF groups than in the no-HF group. The annual stroke/SE incidence rates were 2.8%, 0.7%, 1.1%, and 0.9% in the HFpEF, HFmrEF, HFrEF, and no-HF groups, respectively. The cumulative incidence of stroke/SE was significantly highest in the HFpEF group at 22.8 ± 10.0 months (P = 0.020). The stroke/SE risk was higher in the HFpEF group than in the HFmrEF and HFrEF groups (hazard ratio, 3.192; 95% confidence interval, 1.039–9.810; P = 0.043). E/e' value was an independent risk factor for stroke/SE. There were no significant differences in the incidence of major bleeding across the groups. Conclusions: The stroke/SE risk was the highest in the HFpEF group and comparable between the HFmrEF and HFrEF groups. © 2021 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology. | * |
dc.description.sponsorship | Uhm, J.-S.; Division of Cardiology, 50-1 Yonsei-ro Seodaemun-gu, South Korea; email: jason@yuhs.ac Joung, B.; Division of Cardiology, 50-1 Yonsei-ro Seodaemun-gu, South Korea; email: cby6908@yuhs.ac | * |
dc.language | English | * |
dc.publisher | John Wiley and Sons Inc | * |
dc.subject | Atrial fibrillation | * |
dc.subject | Bleeding | * |
dc.subject | Ejection fraction | * |
dc.subject | Heart failure | * |
dc.subject | Stroke | * |
dc.subject | Systemic embolism | * |
dc.title | Stroke and systemic embolism in patients with atrial fibrillation and heart failure according to heart failure type | * |
dc.type | Article | * |
dc.relation.issue | 2 | * |
dc.relation.volume | 8 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 1582 | * |
dc.relation.lastpage | 1589 | * |
dc.relation.journaltitle | ESC Heart Failure | * |
dc.identifier.doi | 10.1002/ehf2.13264 | * |
dc.identifier.wosid | WOS:000621734400001 | * |
dc.identifier.scopusid | 2-s2.0-85101615610 | * |
dc.author.google | Uhm J.-S. | * |
dc.author.google | Kim J. | * |
dc.author.google | Yu H.T. | * |
dc.author.google | Kim T.-H. | * |
dc.author.google | Lee S.-R. | * |
dc.author.google | Cha M.-J. | * |
dc.author.google | Choi E.-K. | * |
dc.author.google | Lee J.M. | * |
dc.author.google | Kim J.-B. | * |
dc.author.google | Park J. | * |
dc.author.google | Park J.-K. | * |
dc.author.google | Kang K.-W. | * |
dc.author.google | Shim J. | * |
dc.author.google | Park H.W. | * |
dc.author.google | Lee Y.S. | * |
dc.author.google | Kim C.-S. | * |
dc.author.google | Mun J.E. | * |
dc.author.google | Son N.-H. | * |
dc.author.google | Joung B. | * |
dc.contributor.scopusid | 박준범(55131469900) | * |
dc.date.modifydate | 20240429132147 | * |