Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 신상훈 | - |
dc.contributor.author | 이상은 | - |
dc.date.accessioned | 2021-05-17T16:30:59Z | - |
dc.date.available | 2021-05-17T16:30:59Z | - |
dc.date.issued | 2021 | - |
dc.identifier.issn | 0021-9150 | - |
dc.identifier.other | OAK-29242 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/257326 | - |
dc.description.abstract | Background and aims: The atherogenic index of plasma (AIP) has been suggested as a marker of plasma atherogenicity. This study aimed to assess the association between AIP and the rapid progression of coronary atherosclerosis using serial coronary computed tomography angiography (CCTA). Methods: A total of 1488 adults (60.9 ± 9.2 years, 58.9% male) who underwent serial CCTA with a median inter-scan period of 3.4 years were included. AIP was defined as the base 10 logarithm of the ratio of the concentrations of triglyceride to high-density lipoprotein cholesterol. Rapid plaque progression (RPP) was defined as the change of percentage atheroma volume (PAV) ≥1.0%/year. All participants were divided into three groups based on AIP tertiles. Results: Baseline total PAV (median [interquartile range (IQR)]) (%) (group I [lowest]: 1.91 [0.00, 6.21] vs. group II: 2.82 [0.27, 8.83] vs. group III [highest]: 2.70 [0.41, 7.50]), the annual change of total PAV (median [IQR]) (%/year) (group I: 0.27 [0.00, 0.81] vs. group II: 0.37 [0.04, 1.11] vs. group III: 0.45 [0.06, 1.25]), and the incidence of RPP (group I: 19.7% vs. group II: 27.3% vs. group III: 31.4%) were significantly different among AIP tertiles (all p < 0.05). In multiple logistic regression analysis, the risk of RPP was increased in group III (odds ratio: 1.52, 95% confidence interval: 1.02–2.26; p = 0.042) compared to group I after adjusting for clinical factors and baseline total PAV. Conclusions: Based on serial CCTA findings, AIP is an independent predictive marker for RPP beyond traditional risk factors. © 2021 Elsevier B.V. | - |
dc.language | English | - |
dc.publisher | Elsevier Ireland Ltd | - |
dc.subject | Atherogenic index of plasma | - |
dc.subject | Atherosclerosis | - |
dc.subject | Coronary artery disease | - |
dc.subject | Coronary computed tomography angiography | - |
dc.title | Atherogenic index of plasma and the risk of rapid progression of coronary atherosclerosis beyond traditional risk factors | - |
dc.type | Article | - |
dc.relation.volume | 324 | - |
dc.relation.index | SCIE | - |
dc.relation.index | SCOPUS | - |
dc.relation.startpage | 46 | - |
dc.relation.lastpage | 51 | - |
dc.relation.journaltitle | Atherosclerosis | - |
dc.identifier.doi | 10.1016/j.atherosclerosis.2021.03.009 | - |
dc.identifier.wosid | WOS:000645464100006 | - |
dc.identifier.scopusid | 2-s2.0-85103571358 | - |
dc.author.google | Won K.-B. | - |
dc.author.google | Heo R. | - |
dc.author.google | Park H.-B. | - |
dc.author.google | Lee B.K. | - |
dc.author.google | Lin F.Y. | - |
dc.author.google | Hadamitzky M. | - |
dc.author.google | Kim Y.-J. | - |
dc.author.google | Sung J.M. | - |
dc.author.google | Conte E. | - |
dc.author.google | Andreini D. | - |
dc.author.google | Pontone G. | - |
dc.author.google | Budoff M.J. | - |
dc.author.google | Gottlieb I. | - |
dc.author.google | Chun E.J. | - |
dc.author.google | Cademartiri F. | - |
dc.author.google | Maffei E. | - |
dc.author.google | Marques H. | - |
dc.author.google | de Araújo Gonçalves P. | - |
dc.author.google | Leipsic J.A. | - |
dc.author.google | Lee S.-E. | - |
dc.author.google | Shin S. | - |
dc.author.google | Choi J.H. | - |
dc.author.google | Virmani R. | - |
dc.author.google | Samady H. | - |
dc.author.google | Chinnaiyan K. | - |
dc.author.google | Berman D.S. | - |
dc.author.google | Narula J. | - |
dc.author.google | Shaw L.J. | - |
dc.author.google | Bax J.J. | - |
dc.author.google | Min J.K. | - |
dc.author.google | Chang H.-J. | - |
dc.contributor.scopusid | 신상훈(7403646689) | - |
dc.contributor.scopusid | 이상은(57213176330) | - |
dc.date.modifydate | 20230208112553 | - |