Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 태정현 | * |
dc.date.accessioned | 2021-02-04T16:31:07Z | - |
dc.date.available | 2021-02-04T16:31:07Z | - |
dc.date.issued | 2021 | * |
dc.identifier.issn | 1436-3291 | * |
dc.identifier.issn | 1436-3305 | * |
dc.identifier.other | OAK-28616 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/256885 | - |
dc.description.abstract | Background This study aimed to investigate risk factors for lymph node (LN) or distant metastasis after non-curative endoscopic resection (ER) of undifferentiated-type early gastric cancer (EGC). Methods Of 1124 patients who underwent ER for undifferentiated-type gastric cancer at 18 tertiary hospitals across six geographic areas in Korea between 2005 and 2014, 634 with non-curative ER beyond the expanded criteria were retrospectively enrolled. According to the treatment after ER, patients were divided into additional surgery (n = 270) and follow-up (n = 364) groups. The median follow-up duration was 59 months for recurrence and 84 months for mortality. Results LN metastasis was found in 6.7% (18/270) of patients at surgery. Ulcer [odds ratio (OR) 3.83; 95% confidence interval (CI) 1.21-12.13; p=0.022] and submucosal invasion (OR 10.35; 95% CI 1.35-79.48; p=0.025) were independent risk factors. In the follow-up group, seven patients (1.9%) developed LN or distant recurrence. Ulcer [hazard ratio (HR) 7.60; 95% CI 1.39-35.74; p = 0.018], LVI (HR 6.80; 95% CI 1.07-42.99; p = 0.042), and positive vertical margin (HR 6.71; 95% CI 1.28-35.19; p = 0.024) were independent risk factors. In the overall cohort, LN metastasis rates were 9.6% in patients with two or more risk factors and 1.2% in those with no or one risk factor. Conclusions LVI, ulcer, submucosal invasion, and positive vertical margin are independently associated with LN or distant metastasis after non-curative ER of undifferentiated-type EGC. Surgical resection is strongly recommended for patients with two or more risk factors. | * |
dc.language | English | * |
dc.publisher | SPRINGER | * |
dc.subject | Stomach neoplasms | * |
dc.subject | Undifferentiated-type histology | * |
dc.subject | Non-curative resection | * |
dc.subject | Lymph node Metastasis | * |
dc.subject | Risk factors | * |
dc.title | Risk factors of lymph node metastasis after non-curative endoscopic resection of undifferentiated-type early gastric cancer | * |
dc.type | Article | * |
dc.relation.issue | 1 | * |
dc.relation.volume | 24 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 168 | * |
dc.relation.lastpage | 178 | * |
dc.relation.journaltitle | GASTRIC CANCER | * |
dc.identifier.doi | 10.1007/s10120-020-01103-2 | * |
dc.identifier.wosid | WOS:000545310300002 | * |
dc.identifier.scopusid | 2-s2.0-85087445098 | * |
dc.author.google | Yang, Hyo-Joon | * |
dc.author.google | Jang, Jae-Young | * |
dc.author.google | Kim, Sang Gyun | * |
dc.author.google | Ahn, Ji Yong | * |
dc.author.google | Nam, Su Youn | * |
dc.author.google | Kim, Jie-Hyun | * |
dc.author.google | Min, Byung-Hoon | * |
dc.author.google | Lee, Wan-Sik | * |
dc.author.google | Lee, Bong Eun | * |
dc.author.google | Joo, Moon Kyung | * |
dc.author.google | Park, Jae Myung | * |
dc.author.google | Shin, Woon Geon | * |
dc.author.google | Lee, Hang Lak | * |
dc.author.google | Gweon, Tae-Geun | * |
dc.author.google | Park, Moo In | * |
dc.author.google | Choi, Jeongmin | * |
dc.author.google | Tae, Chung Hyun | * |
dc.author.google | Kim, Young-Il | * |
dc.author.google | Choi, Il Ju | * |
dc.contributor.scopusid | 태정현(35211966400) | * |
dc.date.modifydate | 20240308140308 | * |