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Oral health and changes in lipid profile: A nationwide cohort study
- Title
- Oral health and changes in lipid profile: A nationwide cohort study
- Authors
- Song T.-J.; Kim J.-W.; Kim J.
- Ewha Authors
- 송태진; 김진우
- SCOPUS Author ID
- 송태진; 김진우
- Issue Date
- 2020
- Journal Title
- Journal of Clinical Periodontology
- ISSN
- 0303-6979
- Citation
- Journal of Clinical Periodontology vol. 47, no. 12, pp. 1437 - 1445
- Keywords
- dyslipidaemia; oral hygiene; periodontal diseases; toothbrushing; triglyceride
- Publisher
- Blackwell Munksgaard
- Indexed
- SCIE; SCOPUS
- Document Type
- Article
- Abstract
- Aim: We aimed to investigate the association of periodontitis and oral hygiene indicators with changes in blood lipid parameters in a nationwide, population-based cohort in a longitudinal setting. Materials and methods: We included nationwide health screening program participants who underwent oral health examination in 2009-2010 and follow-up examinations for lipid profile without exposure to lipid-lowering agents. Results: During the 5.19-year median follow-up, 65,078 individuals (mean age at baseline examination: 55.41 ± 7.30 years) underwent 286,218 health examinations. The prevalence of periodontitis was 39%. In the multivariate mixed model analysis, periodontitis and tooth loss were associated with decreased high-density lipoprotein cholesterol levels (β = −0.0066 mmol/L, standard error = 0.0026, p =.013) and increased triglyceride levels (β=0.0307, mmol/L, standard error = 0.0049, p <.001), respectively. Compared with tooth brushing ≤1 time/day, tooth brushing ≥3 times/day was associated with increased high-density lipoprotein cholesterol levels (β = 0.0176 mmol/L, standard error = 0.0052, p =.006) and decreased triglyceride levels (β = −0.0285 mmol/L, standard error = 0.0090, p =.001). Conclusions: Periodontitis and tooth loss may be attenuating factors for blood high-density lipoprotein cholesterol and triglyceride levels, respectively. Frequent tooth brushing may improve dyslipidaemia, particularly blood high-density lipoprotein cholesterol and triglyceride levels. Oral hygiene improvement may reduce the risk of dyslipidaemia. © 2020 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd
- DOI
- 10.1111/jcpe.13373
- Appears in Collections:
- 의과대학 > 의학과 > Journal papers
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